Literature DB >> 8370358

The hibernating myocardium in ischaemia and congestive heart failure.

S H Rahimtoola1.   

Abstract

Hibernating myocardium refers to the presence of persistent myocardial and left ventricular dysfunction at rest due to reduced coronary blood flow that can be partially or completely restored to normal by myocardial revascularization. An increasing amount of data show it is most likely a downgrading of cardiac function so that blood flow and myocardial function are once again in a state of equilibrium. It has been demonstrated to occur in patients with unstable angina, chronic stable angina, acute myocardial infarction and in left ventricular dysfunction and/or congestive heart failure. Salvage of this viable myocardium by successful revascularization improves left ventricular dysfunction and probably also patient survival. Therefore, diagnosis of hibernating myocardium is important because it does not render left ventricular dysfunction a necessary contraindication to revascularization, nor does it leave the patient with chronic heart failure a candidate only for cardiac transplantation. Instead, these patients should have complete revascularization by coronary bypass surgery/percutaneous transluminal coronary angioplasty as soon as possible.

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Year:  1993        PMID: 8370358     DOI: 10.1093/eurheartj/14.suppl_a.22

Source DB:  PubMed          Journal:  Eur Heart J        ISSN: 0195-668X            Impact factor:   29.983


  8 in total

1.  Detection of scarred and viable myocardium using a new magnetic resonance imaging technique: blood oxygen level dependent (BOLD) MRI.

Authors:  M Egred; A Al-Mohammad; G D Waiter; T W Redpath; S K Semple; M Norton; A Welch; S Walton
Journal:  Heart       Date:  2003-07       Impact factor: 5.994

2.  The extracellular matrix in hibernating myocardium--a significant factor causing structural defects and cardiac dysfunction.

Authors:  A Elsässer; M Schlepper; R Zimmermann; K D Müller; R Strasser; W P Klövekorn; J Schaper
Journal:  Mol Cell Biochem       Date:  1998-09       Impact factor: 3.396

Review 3.  Molecular and cellular basis of viable dysfunctional myocardium.

Authors:  Marina Bayeva; Konrad Teodor Sawicki; Javed Butler; Mihai Gheorghiade; Hossein Ardehali
Journal:  Circ Heart Fail       Date:  2014-07       Impact factor: 8.790

Review 4.  Prevention of relapse in patients with congestive heart failure: the role of precipitating factors.

Authors:  J Feenstra; D E Grobbee; F A Jonkman; A W Hoes; B H Stricker
Journal:  Heart       Date:  1998-11       Impact factor: 5.994

Review 5.  Heart failure following anterior myocardial infarction: an indication for ventricular restoration, a surgical method to reverse post-infarction remodeling.

Authors:  Alfred W H Stanley; Constantine L Athanasuleas; Gerald D Buckberg
Journal:  Heart Fail Rev       Date:  2004-10       Impact factor: 4.214

Review 6.  Myocardial revascularization as a therapeutic strategy in the patient with advanced ventricular dysfunction.

Authors:  F A Mitropoulos; J A Elefteriades
Journal:  Heart Fail Rev       Date:  2001-09       Impact factor: 4.214

7.  A self-perpetuating vicious cycle of tissue damage in human hibernating myocardium.

Authors:  A Elsässer; E Decker; S Kostin; S Hein; W Skwara; K D Müller; S Greiber; W Schaper; W P Klövekorn; J Schaper
Journal:  Mol Cell Biochem       Date:  2000-10       Impact factor: 3.396

8.  Long-term prognostic value of stress-redistribution-reinjection Tl-201 imaging in patients with severe left ventricular dysfunction and coronary artery bypass surgery.

Authors:  Metin Gürsürer; Ayşe Emre; Hakan Gerçekoğlu; Seyfi Uslubaş; Mehmet Aksoy; Birsen Ersek
Journal:  Int J Cardiovasc Imaging       Date:  2002-04       Impact factor: 2.357

  8 in total

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