Literature DB >> 8370115

Cytotoxic sesquiterpenes from Nardostachys chinensis.

H Itokawa1, K Masuyama, H Morita, K Takeya.   

Abstract

Five cytostatic sesquiterpenes, desoxo-narchinol-A (1), nardosinone (2), debilon (3), nardosinonediol (4) and kanshone A (5), were isolated from the roots and rhizomes of Nardostachys chinensis (Valerianaceae). The steric structure of 1 was determined by nuclear Overhauser effects (NOEs) and the exciton chirality method. All five showed cytotoxic activity against P-388 cells and the structure-activity relationship of 1 was also discussed.

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Year:  1993        PMID： 8370115     DOI： 10.1248/cpb.41.1183

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  10 in total

1.  Comparative study on volatile components of Nardostachys rhizome.

Authors:  Ken Tanaka; Katsuko Komatsu
Journal:  J Nat Med       Date:  2007-10-06       Impact factor: 2.343

2.  Sedative effects of vapor inhalation of agarwood oil and spikenard extract and identification of their active components.

Authors:  Hiroaki Takemoto; Michiho Ito; Tomohiro Shiraki; Toru Yagura; Gisho Honda
Journal:  J Nat Med       Date:  2007-08-23       Impact factor: 2.343

3.  Nardosinone-Type Sesquiterpenes from the Hexane Fraction of Nardostachys jatamansi Attenuate NF-κB and MAPK Signaling Pathways in Lipopolysaccharide-Stimulated BV2 Microglial Cells.

Authors:  Wonmin Ko; Jin-Soo Park; Kwan-Woo Kim; Jongwon Kim; Youn-Chul Kim; Hyuncheol Oh
Journal:  Inflammation       Date:  2018-08       Impact factor: 4.092

4.  Red Algae (Rhodophyta) from the Coast of Madagascar: Preliminary Bioactivity Studies and Isolation of Natural Products.

Authors:  Marie Pascaline Rahelivao; Margit Gruner; Hanta Andriamanantoanina; Bakolinirina Andriamihaja; Ingmar Bauer; Hans-Joachim Knölker
Journal:  Mar Drugs       Date:  2015-07-07       Impact factor: 5.118

Review 5.  The cardioprotective and antiarrhythmic effects of Nardostachys chinensis in animal and cell experiments.

Authors:  Min Li; Xue Xu; Xinyu Yang; Joey S W Kwong; Hongcai Shang
Journal:  BMC Complement Altern Med       Date:  2017-08-10       Impact factor: 3.659

6.  Chemical analysis and biological activity of the essential oils of two valerianaceous species from China: Nardostachys chinensis and Valeriana officinalis.

Authors:  Jihua Wang; Jianglin Zhao; Hao Liu; Ligang Zhou; Zhilong Liu; Jingguo Wang; Jianguo Han; Zhu Yu; Fuyu Yang
Journal:  Molecules       Date:  2010-09-14       Impact factor: 4.411

7.  Aristolane-type Sesquiterpenoids from Nardostachys chinensis and Revised Structure of Aristolanhydride.

Authors:  Li-Xia Wang; Xian-Jun Jiang; Xiang-Mei Li; Mei-Fen Mao; Guo-Zhu Wei; Fei Wang
Journal:  Nat Prod Bioprospect       Date:  2019-03-08

8.  Chemical Analysis of the Ingredients of 20% Aqueous Ethanol Extract of Nardostachys jatamansi through Phytochemical Study and Evaluation of Anti-Neuroinflammatory Component.

Authors:  Kwan-Woo Kim; Chi-Su Yoon; Sung-Joo Park; Gi-Sang Bae; Dong-Gu Kim; Youn-Chul Kim; Hyuncheol Oh
Journal:  Evid Based Complement Alternat Med       Date:  2021-04-22       Impact factor: 2.629

9.  Novel serotonin transporter regulators: Natural aristolane- and nardosinane- types of sesquiterpenoids from Nardostachys chinensis Batal.

Authors:  Ying-Peng Chen; Shu-Song Ying; Hong-Hong Zheng; Yan-Ting Liu; Zhong-Ping Wang; Hu Zhang; Xu Deng; Yi-Jing Wu; Xiu-Mei Gao; Tian-Xiang Li; Yan Zhu; Yan-Tong Xu; Hong-Hua Wu
Journal:  Sci Rep       Date:  2017-11-08       Impact factor: 4.379

Review 10.  Structures, Occurrences and Biosynthesis of 11,12,13-Tri-nor-Sesquiterpenes, an Intriguing Class of Bioactive Metabolites.

Authors:  Víctor Coca-Ruíz; Ivonne Suárez; Josefina Aleu; Isidro G Collado
Journal:  Plants (Basel)       Date:  2022-03-14
  10 in total

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