L C Cheng1, Y M Salmon. 1. Academic Department of Obstetrics and Gynaecology, King's College School of Medicine and Dentistry, London.
Abstract
OBJECTIVE: To determine the normal response to a 75 g glucose challenge in the context of an oral glucose tolerance test in the third trimester of pregnancy. DESIGN: Prospective observational study. SETTING: Antenatal clinic, Kandang Kerbau Hospital, Singapore. SUBJECTS: Sixty-four normal pregnant women with a low risk for diabetes. INTERVENTIONS: Glucose (75 g) challenge following an overnight fast after 28 weeks of gestation. MAIN OUTCOME MEASURE: Venous plasma glucose levels taken before and 2 h after the glucose challenge. RESULTS: Upper limits of normality were found to be fasting glucose 4.9 mmol/l and 2 h glucose 9.2 mmol/l. CONCLUSION: The WHO (1980) criteria should not be used in pregnancy.
OBJECTIVE: To determine the normal response to a 75 g glucose challenge in the context of an oral glucose tolerance test in the third trimester of pregnancy. DESIGN: Prospective observational study. SETTING: Antenatal clinic, Kandang Kerbau Hospital, Singapore. SUBJECTS: Sixty-four normal pregnant women with a low risk for diabetes. INTERVENTIONS:Glucose (75 g) challenge following an overnight fast after 28 weeks of gestation. MAIN OUTCOME MEASURE: Venous plasma glucose levels taken before and 2 h after the glucose challenge. RESULTS: Upper limits of normality were found to be fasting glucose 4.9 mmol/l and 2 h glucose 9.2 mmol/l. CONCLUSION: The WHO (1980) criteria should not be used in pregnancy.
Entities:
Keywords:
Asia; Asians; Biology; Birth Weight; Body Weight; Cultural Background; Demographic Factors; Developing Countries; Diabetes Mellitus; Diseases; Ethnic Groups; Examinations And Diagnoses; Glucose Tolerance Test; International Agencies; Laboratory Examinations And Diagnoses; Laboratory Procedures; Organizations; Physiology; Population; Population Characteristics; Pregnancy; Pregnancy, Third Trimester; Reproduction; Research Methodology; Risk Factors; Singapore; Southeastern Asia; Statistical Studies; Studies; Un; Who