Glucocorticoid receptors in corticosensitive and corticoresistant thymocyte subpopulations. II. Studies with hydrocortisone-treated mice.

In vitro studies of the residual thymocyte population isolated 48 h after in vivo hydrocortisone injection showed: 1. These cells are partly sensitive to steroid as demonstrated by uridine incorporation inhibition. 2. This residual cell fraction appears heterogeneous after centrifugation on a bovine serum albumine gradient. 3. These cells exhibit low steroid binding and DNA synthesis capacities.