Literature DB >> 8368157

Recombinant Aspergillus fumigatus allergen I/a (rAsp f I/a) in the diagnosis of Aspergillus related diseases.

M Moser1, R Crameri, G Menz, M Suter.   

Abstract

A. fumigatus allergen I/a (rAsp f I/a) was produced in Escherichia coli, affinity purified by Ni(2+)-chelate chromatography and refolded. rAsp f I/a binds IgE of A. fumigatus-allergic individuals as shown by ELISA, dot blots and Western blots. In addition, rAsp I/a elicited positive immediate type I skin reactions in individuals allergic to A. fumigatus but not in control individuals. Hence, rAsp f I/a can be used as a standardized antigen/allergen for an improved serological and clinical diagnosis of A. fumigatus-associated diseases.

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Year:  1993        PMID: 8368157     DOI: 10.1007/978-3-0348-7324-6_11

Source DB:  PubMed          Journal:  Agents Actions Suppl        ISSN: 0379-0363


  2 in total

1.  Recombinant expression and antigenic properties of a 32-kilodalton extracellular alkaline protease, representing a possible virulence factor from Aspergillus fumigatus.

Authors:  M Moser; G Menz; K Blaser; R Crameri
Journal:  Infect Immun       Date:  1994-03       Impact factor: 3.441

Review 2.  The allergenic activity and clinical impact of individual IgE-antibody binding molecules from indoor allergen sources.

Authors:  Luis Caraballo; Rudolf Valenta; Leonardo Puerta; Anna Pomés; Josefina Zakzuk; Enrique Fernandez-Caldas; Nathalie Acevedo; Mario Sanchez-Borges; Ignacio Ansotegui; Luo Zhang; Marianne van Hage; Eva Fernández; Luisa Arruda; Susanne Vrtala; Mirela Curin; Hans Gronlund; Antonina Karsonova; Jonathan Kilimajer; Ksenja Riabova; Daria Trifonova; Alexander Karaulov
Journal:  World Allergy Organ J       Date:  2020-04-29       Impact factor: 4.084

  2 in total

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