Literature DB >> 8367438

[Intracranial cavernoma. 30 cases].

M Lonjon1, J L Roche, B George, K L Mourier, P Paquis, G Lot, P Grellier.   

Abstract

During the last few years, as a result of improved neurodiagnostic procedure there has been an increase in the number of intracranial cavernous angioma. We present 30 cases totalling 32 cavernous angiomas. Twenty-one received a successful surgical treatment. Twenty-four angiomas were supratentorial (75 percent) and 8 subtentorial (25 percent). Cavernous angiomas are congenital vascular malformations, usually of small size, with multiple vascular cavities surrounded by fibrous walls. They are often found in young adults (mean age 35 years in our series), most frequently located in the supratentorial white matter. The presenting symptoms were epilepsy, haemorrhage and an expanding mass syndrome. In this series, 16 patients had epilepsy (53 percent), 7 had haemorrhage (23.5 percent) and 7 had a mass syndrome (23.5 percent). The diagnosis of this lesion, usually obtained with angiography, has been dramatically improved by CT scan and, particularly, MRI. The natural history of cavernous angiomas is still poorly understood: the major complication is haemorrhage. Total surgical excision is the treatment of choice: it avoids a possible haemorrhage and is effective in relieving epileptic seizures. The indication for surgery depends on the clinical symptom and the location of the lesion. The post-operative morbidity in our 21 operated cases was fairly low due to minor sequelae. In only 2 of the 16 patients who had epilepsy the clinical seizures persisted after surgery, but they were less frequent. The literature is reviewed.

Entities:  

Mesh:

Year:  1993        PMID: 8367438

Source DB:  PubMed          Journal:  Presse Med        ISSN: 0755-4982            Impact factor:   1.228


  6 in total

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Journal:  J Neurol Neurosurg Psychiatry       Date:  1995-12       Impact factor: 10.154

2.  Population-Based Prevalence of Cerebral Cavernous Malformations in Older Adults: Mayo Clinic Study of Aging.

Authors:  Kelly D Flemming; Jonathan Graff-Radford; Jeremiah Aakre; Kejal Kantarci; Giuseppe Lanzino; Robert D Brown; Michelle M Mielke; Rosebud O Roberts; Walter Kremers; David S Knopman; Ronald C Petersen; Clifford R Jack
Journal:  JAMA Neurol       Date:  2017-07-01       Impact factor: 18.302

3.  Familial cavernous hemangioma with atypical neuroimaging.

Authors:  M G Passarin; A Salviati; G Gambina; F Tezzon; G Tomelleri; L Deotto; T Zanoni; P Bovi; M Gerosa; A Nicolato; C Mazza; P Iuzzolino; C Ghimenton; G Ferrari
Journal:  Ital J Neurol Sci       Date:  1996-08

4.  Dura-based cavernous hemangioma presenting as large intracerebral hematoma in a child: A rare clinico-pathological entity.

Authors:  Hariprakash K Chakravarthy; Balamurugan Mangaleshwaran; P Boopesh; Moses M Ambroise; Syed Ali
Journal:  J Pediatr Neurosci       Date:  2011-07

5.  An isolated cavernous malformation of the sixth cranial nerve: A case report and review of literature.

Authors:  Mohammad Samadian; Seyed Farzad Maroufi; Mehrdad Hosseinzadeh Bakhtevari; Hamid Borghei-Razavi
Journal:  Surg Neurol Int       Date:  2021-11-16

6.  Treatment of Nystagmus in Brainstem Cavernous Malformation with Botulinum Toxin.

Authors:  Yi-Ren Chen; Douglas Fredrick; Gary K Steinberg; Yaping J Liao
Journal:  Cureus       Date:  2016-04-01
  6 in total

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