Literature DB >> 8366676

Induction of alloxan/streptozotocin diabetes in dogs: a revised experimental technique.

H R Anderson1, A W Stitt, T A Gardiner, S J Lloyd, D B Archer.   

Abstract

The diabetic dog represents an excellent model for use in many aspects of diabetic research. The present paper describes, in detail, a reproducible experimental protocol for the successful induction of chemical diabetes in beagles using a combination of the 2 pancreatic beta-cell cytoxic agents alloxan and streptozotocin.

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Year:  1993        PMID： 8366676     DOI： 10.1258/002367793780745426

Source DB:  PubMed          Journal:  Lab Anim        ISSN： 0023-6772            Impact factor:   2.471


  11 in total

1.  Gongronema latifolium delays gastric emptying of semi-solid meals in diabetic dogs.

Authors:  Sylvester Osita Ogbu; Kenneth Kalu Agwu; Isaac Uzoma Asuzu
Journal:  Afr J Tradit Complement Altern Med       Date:  2013-08-12

2.  Development of Canine Models of Type 1 Diabetes With Partial Pancreatectomy and the Administration of Streptozotocin.

Authors:  Masayuki Seita; Hirofumi Noguchi; Yasuhiro Kubota; Hironobu Kawamoto; Shuhei Nakaji; Naoya Kobayashi; Toshiyoshi Fujiwara
Journal:  Cell Med       Date:  2013-10-21

3.  Hypoglycemic effects of vanadium on alloxan monohydrate induced diabetic dogs.

Authors:  Joo-Min Kim; Jin-Young Chung; Sook-Yeon Lee; Eun-Wha Choi; Min-Kyu Kim; Cheol-Yong Hwang; Hwa-Young Youn
Journal:  J Vet Sci       Date:  2006-12       Impact factor: 1.672

4.  Prevention of retinal capillary basement membrane thickening in diabetic dogs by a non-steroidal anti-inflammatory drug.

Authors:  T A Gardiner; H R Anderson; T Degenhardt; S R Thorpe; J W Baynes; D B Archer; A W Stitt
Journal:  Diabetologia       Date:  2003-07-12       Impact factor: 10.122

5.  Diabetic retinopathy: quantitative variation in capillary basement membrane thickening in arterial or venous environments.

Authors:  A W Stitt; H R Anderson; T A Gardiner; D B Archer
Journal:  Br J Ophthalmol       Date:  1994-02       Impact factor: 4.638

6.  Selective loss of vascular smooth muscle cells in the retinal microcirculation of diabetic dogs.

Authors:  T A Gardiner; A W Stitt; H R Anderson; D B Archer
Journal:  Br J Ophthalmol       Date:  1994-01       Impact factor: 4.638

Review 7.  Animal Models of Diabetic Retinopathy.

Authors:  Ana Maria Olivares; Kristen Althoff; Gloria Fanghua Chen; Siqi Wu; Margaux A Morrisson; Margaret M DeAngelis; Neena Haider
Journal:  Curr Diab Rep       Date:  2017-08-24       Impact factor: 4.810

8.  Treatment of diabetes and long-term survival after insulin and glucokinase gene therapy.

Authors:  David Callejas; Christopher J Mann; Eduard Ayuso; Ricardo Lage; Iris Grifoll; Carles Roca; Anna Andaluz; Rafael Ruiz-de Gopegui; Joel Montané; Sergio Muñoz; Tura Ferre; Virginia Haurigot; Shangzhen Zhou; Jesús Ruberte; Federico Mingozzi; Katherine A High; Felix Garcia; Fatima Bosch
Journal:  Diabetes       Date:  2013-02-01       Impact factor: 9.461

9.  Insulin-producing Cells from Adult Human Bone Marrow Mesenchymal Stromal Cells Could Control Chemically Induced Diabetes in Dogs: A Preliminary Study.

Authors:  Mahmoud M Gabr; Mahmoud M Zakaria; Ayman F Refaie; Amani M Ismail; Sherry M Khater; Sylvia A Ashamallah; Maha M Azzam; Mohamed A Ghoneim
Journal:  Cell Transplant       Date:  2018-06-04       Impact factor: 4.064

10.  Loss of sympathetic innervation to islets of Langerhans in canine diabetes and pancreatitis is not associated with insulitis.

Authors:  Chen Gilor; Jully Pires; Rachel Greathouse; Rebecca Horn; Mark O Huising; Stanley L Marks; Brian Murphy; Amir Kol
Journal:  Sci Rep       Date:  2020-11-05       Impact factor: 4.379
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