Literature DB >> 836613

[Orally-administered taurine in therapy-resistant epilepsy (author's transl)].

P König, G Kriechbaum, O Presslich, H Schubert, P Schuster, W Sieghart.   

Abstract

The anticonvulsive action of taurine, was tested in 9 therapy in 9 therapy-resistant patients with a high incidence of seizures. Taurine was given orally (1.5-7.5 g daily) over a period of 4 to 16 weeks and, despite the high dosage, no appreciable side effects were observed. During this time seizures disappeared temporarily for about two weeks in 5 out of 9 cases. In one case the seizure frequency was transiently reduced by approximately 25%, whilst in the remaining 3 cases no effect of taurine on seizure frequency was observed. The reason for the rapid disappearance of the anticonvulsive action of taurine is not known.

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Year:  1977        PMID: 836613

Source DB:  PubMed          Journal:  Wien Klin Wochenschr        ISSN: 0043-5325            Impact factor:   1.704


  2 in total

1.  Impaired acquisition and retention of a passive avoidance response after chronic ingestion of taurine.

Authors:  P R Sanberg; H C Fibiger
Journal:  Psychopharmacology (Berl)       Date:  1979-03-29       Impact factor: 4.530

Review 2.  Effects and Mechanisms of Taurine as a Therapeutic Agent.

Authors:  Stephen Schaffer; Ha Won Kim
Journal:  Biomol Ther (Seoul)       Date:  2018-05-01       Impact factor: 4.634

  2 in total

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