Bullous pemphigoid.

Bullous pemphigoid is an acquired subepidermal blistering disease of the elderly characterized by tense blisters. Patients with bullous pemphigoid have circulating and tissue-bound antibodies that are directed against a normal component of the epidermal basement membrane. The course of bullous pemphigoid tends to be self-limited, and effective treatment is often affected with systemic glucocorticosteroids.