| Literature DB >> 836428 |
A G Levis, M Buttignol, L Vettorato.
Abstract
Treatment of hamster fibroblasts with potassium dichromate in vitro stimulates tritiated thymidine uptake into the intracellular nucleotide pool. This effect is due to the oxidizing action of hexavalent chromium on the plasma membrane. Dichromate, induces also an inhibition of DNA replication, which is due to the interaction of reduced trivalent chromium with specific biological ligands on the DNA molecule.Entities:
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Year: 1977 PMID： 836428 DOI： 10.1007/BF01936767
Source DB: PubMed Journal: Experientia ISSN： 0014-4754