Literature DB >> 8363583

Effect of lead acetate and carbon particles on the expression of glutathione S-transferase YfYf in rat liver.

S J Boyce1, T J Mantle.   

Abstract

Administration of intracardiac lead acetate produces a complex response in glutathione S-transferase (GST) YfYf expression in rat liver. The earliest response, an elevation of GST expression in Kupffer cells, can be mimicked by administering a suspension of carbon particles. The second effect of lead acetate administration is a marked elevation of GST YfYf in some but not all hepatocytes (the 'patchy' response). This effect is most marked 48-76 h after administration of a single dose of lead acetate and is easily detected by immunoblotting. Dexamethasone down-regulates the lead response in hepatocytes.

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Year:  1993        PMID： 8363583      PMCID： PMC1134598          DOI： 10.1042/bj2940301

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  28 in total

1.  Glutathione transferase pi its minimal promoter and downstream cis-acting element.

Authors:  C L Xia; I G Cowell; K H Dixon; S E Pemble; B Ketterer; J B Taylor
Journal:  Biochem Biophys Res Commun       Date:  1991-04-15       Impact factor: 3.575

2.  The development of glutathione S-transferase subunits in rat liver. Sensitive detection of the major subunit forms of rat glutathione S-transferase by using an e.l.i.s.a. method.

Authors:  F M McCusker; S J Boyce; T J Mantle
Journal:  Biochem J       Date:  1989-09-01       Impact factor: 3.857

3.  A new method to monitor Kupffer-cell function continuously in the perfused rat liver. Dissociation of glycogenolysis from particle phagocytosis.

Authors:  K B Cowper; R T Currin; T L Dawson; K A Lindert; J J Lemasters; R G Thurman
Journal:  Biochem J       Date:  1990-02-15       Impact factor: 3.857

4.  The human glutathione S-transferases. Immunohistochemical studies of the developmental expression of Alpha- and Pi-class isoenzymes in liver.

Authors:  C Hiley; A Fryer; J Bell; R Hume; R C Strange
Journal:  Biochem J       Date:  1988-08-15       Impact factor: 3.857

5.  The structure of the human glutathione S-transferase pi gene.

Authors:  I G Cowell; K H Dixon; S E Pemble; B Ketterer; J B Taylor
Journal:  Biochem J       Date:  1988-10-01       Impact factor: 3.857

6.  Theta, a new class of glutathione transferases purified from rat and man.

Authors:  D J Meyer; B Coles; S E Pemble; K S Gilmore; G M Fraser; B Ketterer
Journal:  Biochem J       Date:  1991-03-01       Impact factor: 3.857

Review 7.  Glutathione transferases and cancer.

Authors:  S Tsuchida; K Sato
Journal:  Crit Rev Biochem Mol Biol       Date:  1992       Impact factor: 8.250

8.  Suppression of glutathione transferase P expression by glucocorticoid.

Authors:  M Sakai; M Muramatsu; S Nishi
Journal:  Biochem Biophys Res Commun       Date:  1992-09-16       Impact factor: 3.575

9.  Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in the rat glutathione transferase P gene.

Authors:  A Okuda; M Imagawa; Y Maeda; M Sakai; M Muramatsu
Journal:  J Biol Chem       Date:  1989-10-05       Impact factor: 5.157

10.  Induction of rat liver glutathione transferase subunit 7 by lead nitrate.

Authors:  C Di Ilio; A Aceto; A Columbano; G M Ledda-Columbano; G Federici
Journal:  Cancer Lett       Date:  1989-08       Impact factor: 8.679
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