| Literature DB >> 8363388 |
W B Offensperger1, S Offensperger, E Walter, H E Blum, W Gerok.
Abstract
The effect of suramin on duck hepatitis B virus (DHBV) infection was investigated in vivo. Suramin pretreatment of Pekin ducklings completely prevented DHBV infection. In contrast, suramin given at the time of or after inoculation with DHBV did not inhibit viral infection, replication, or gene expression. These data indicate that suramin effectively blocks the early stages of DHBV infection in vivo.Entities:
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Year: 1993 PMID: 8363388 PMCID: PMC188009 DOI: 10.1128/AAC.37.7.1539
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191