| Literature DB >> 8362219 |
K Haruma1, M Yoshihara, K Sumii, A Tari, C Watanabe, A Kodoi, G Kajiyama.
Abstract
We determined the maximum secretion of gastric acid and the fasting serum levels of pepsinogen I and gastrin in Japanese patients with gastric hyperplastic polyps or polypoid-type early gastric carcinoma, comparing those findings with observations in control subjects. Both the maximum acid secretion and fasting levels of serum pepsinogen I were significantly lower in the patients with gastric hyperplastic polyps or polypoid-type early gastric carcinoma than in the controls. Fasting serum gastrin levels were significantly higher in the patients with gastric hyperplastic polyps than in the other two groups of subjects. These data demonstrated that the combination of hypochlorhydria, a low level of pepsinogen I, and hypergastrinemia (type-A gastritis) was common in the patients with gastric hyperplastic polyps, whereas hypochlorhydria and a low pepsinogen I without hypergastrinemia (type-B gastritis) were common in those with polypoid-type early gastric carcinoma.Entities:
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Year: 1993 PMID： 8362219 DOI： 10.3109/00365529309096102
Source DB: PubMed Journal: Scand J Gastroenterol ISSN： 0036-5521 Impact factor: 2.423