Literature DB >> 8360713

Methotrexate induced brain necrosis and severe leukoencephalopathy due to disconnection of an Ommaya device.

R de Waal1, P R Algra, J J Heimans, J G Wolbers, P Scheltens.   

Abstract

A 63-year old woman with breast carcinoma developed leucoencephalopathy and local brain necrosis after intraparenchymal infusion of methotrexate. This iatrogenic condition was caused by drain disconnection of the Ommaya device (bore hole type). The diagnosis of this rare complication of an Ommaya device was based on multiplanar MR-imaging. The case is discussed with regard to the complications of intraventricular chemotherapy by means of an Ommaya reservoir.

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Year:  1993        PMID： 8360713     DOI： 10.1007/bf01050074

Source DB:  PubMed          Journal:  J Neurooncol        ISSN： 0167-594X            Impact factor:   4.130


  15 in total

1.  Subcutaneous reservoir and pump for sterile access to ventricular cerebrospinal fluid.

Authors:  A K Ommaya
Journal:  Lancet       Date:  1963-11-09       Impact factor: 79.321

2.  Reservoirs for intraventricular chemotherapy.

Authors:  A S Spiers; A E Booth
Journal:  Lancet       Date:  1973-06-02       Impact factor: 79.321

Review 3.  Complications associated with Ommaya reservoirs in patients with cancer. The Princess Margaret Hospital experience and a review of the literature.

Authors:  M Lishner; R G Perrin; R Feld; H A Messner; P G Tuffnell; T Elhakim; A Matlow; J E Curtis
Journal:  Arch Intern Med       Date:  1990-01

4.  The Ommaya reservoir in chemotherapy for malignant disease in the CNS.

Authors:  A Jacobs; P Clifford; H E Kay
Journal:  Clin Oncol       Date:  1981-06

5.  Hemiparkinsonism as a complication of an Ommaya reservoir. Case report.

Authors:  W P Cheshire; A L Ehle
Journal:  J Neurosurg       Date:  1990-11       Impact factor: 5.115

6.  [Focal cerebral necrosis caused by intraventricular chemotherapy with methotrexate].

Authors:  P A Uldry; D Teta; L Regli
Journal:  Neurochirurgie       Date:  1991       Impact factor: 1.553

7.  Meningeal carcinomatosis in breast cancer. Prognostic factors and influence of treatment.

Authors:  W Boogerd; A A Hart; J J van der Sande; E Engelsman
Journal:  Cancer       Date:  1991-03-15       Impact factor: 6.860

8.  CSF drug levels for children with acute lymphoblastic leukemia treated by 5 g/m2 methotrexate. A study from the EORTC Children's Leukemia Cooperative Group.

Authors:  G Milano; A Thyss; F Serre Debeauvais; G Laureys; Y Benoit; A Deville; C Dutour; A Robert; J Otten; C Behar
Journal:  Eur J Cancer       Date:  1990-04       Impact factor: 9.162

9.  The Ommaya reservoir: newly recognized complications and recommendations for insertion and use.

Authors:  W A Bleyer; P A Pizzo; A M Spence; W D Platt; D R Benjamin; C J Kolins; D G Poplack
Journal:  Cancer       Date:  1978-06       Impact factor: 6.860

10.  Leukoencephalopathy complicating intraventricular catheters: clinical, radiographic and pathologic study of 10 cases.

Authors:  W Lemann; R G Wiley; J B Posner
Journal:  J Neurooncol       Date:  1988       Impact factor: 4.130
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  4 in total

1.  Complications related to the placement of an intraventricular chemotherapy device.

Authors:  Fahed Zairi; Emilie Le Rhun; Marie Charlotte Tetard; Nuria Kotecki; Richard Assaker
Journal:  J Neurooncol       Date:  2010-11-25       Impact factor: 4.130

Review 2.  Toxicity of treatment for neoplastic meningitis.

Authors:  Tali Siegal
Journal:  Curr Oncol Rep       Date:  2003-01       Impact factor: 5.075

3.  Real-Time Fluoroscopic and C-Arm Computed Tomography Evaluation of Ommaya Reservoir Integrity.

Authors:  Adrienne M Moraff; Melanie Hayden Gephart; Larry M Shuer; Jeremy J Heit
Journal:  Cureus       Date:  2017-03-15

Review 4.  Chemotherapy and the pediatric brain.

Authors:  Chrysanthy Ikonomidou
Journal:  Mol Cell Pediatr       Date:  2018-11-06
  4 in total

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