Literature DB >> 8360310

Determination of paraquat in rat brain by high-performance liquid chromatography.

M T Corasaniti1, G Nisticò.   

Abstract

The applications of a method based on ion-pair solid-phase extraction and reversed-phase HPLC are reported. The method was used to measure paraquat concentrations in discrete brain areas at different times after its systemic administration in rats. In addition, the method was employed in the determination of paraquat levels in whole-brain samples from rats of various ages systemically treated with several doses of the herbicide.

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Year:  1993        PMID： 8360310     DOI： 10.1016/0021-9673(93)80578-v

Source DB:  PubMed          Journal:  J Chromatogr


  4 in total

1.  Glycogen synthase kinase 3β and its phosphorylated form (Y216) in the paraquat-induced model of parkinsonism.

Authors:  Martyna Songin; Joanna B Strosznajder; Magdalena Fitał; Katarzyna Kuter; Wacław Kolasiewicz; Przemysław Nowak; Krystyna Ossowska
Journal:  Neurotox Res       Date:  2010-02-09       Impact factor: 3.911

2.  Paraquat is excluded by the blood brain barrier in rhesus macaque: An in vivo pet study.

Authors:  Rachel M Bartlett; James E Holden; R Jerome Nickles; Dhanabalan Murali; David L Barbee; Todd E Barnhart; Bradley T Christian; Onofre T DeJesus
Journal:  Brain Res       Date:  2008-12-24       Impact factor: 3.252

3.  Magnetic Solid-Phase Extraction Using Fe3O4@SiO2 Magnetic Nanoparticles Followed by UV-Vis Spectrometry for Determination of Paraquat in Plasma and Urine Samples.

Authors:  Ou Sha; Yu Wang; Xin Yin; Xiaobing Chen; Li Chen; Shujun Wang
Journal:  J Anal Methods Chem       Date:  2017-07-17       Impact factor: 2.193

4.  Heat shock protein-70 (Hsp-70) suppresses paraquat-induced neurodegeneration by inhibiting JNK and caspase-3 activation in Drosophila model of Parkinson's disease.

Authors:  Arvind Kumar Shukla; Prakash Pragya; Hitesh Singh Chaouhan; Anand Krishna Tiwari; Devendra Kumar Patel; Malik Zainul Abdin; Debapratim Kar Chowdhuri
Journal:  PLoS One       Date:  2014-06-02       Impact factor: 3.240
  4 in total

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