Literature DB >> 8360102

Vicenistatin, a novel 20-membered macrocyclic lactam antitumor antibiotic.

K Shindo1, M Kamishohara, A Odagawa, M Matsuoka, H Kawai.   

Abstract

A new antitumor antibiotic vicenistatin was isolated from the culture broth of Streptomyces sp. HC34. The structure of vicenistatin was elucidated by NMR spectral analysis. Vicenistatin exhibited antitumor activity against human colon carcinoma Co-3 in the xenograft model.

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Year:  1993        PMID： 8360102     DOI： 10.7164/antibiotics.46.1076

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  16 in total

1.  Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis.

Authors:  Akimasa Miyanaga; Shohei Iwasawa; Yuji Shinohara; Fumitaka Kudo; Tadashi Eguchi
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-01       Impact factor: 11.205

Review 2.  Astonishing diversity of natural surfactants: 4. Fatty acid amide glycosides, their analogs and derivatives.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2005-07       Impact factor: 1.880

3.  Mapping Microbial Response Metabolomes for Induced Natural Product Discovery.

Authors:  Dagmara K Derewacz; Brett C Covington; John A McLean; Brian O Bachmann
Journal:  ACS Chem Biol       Date:  2015-06-17       Impact factor: 5.100

4.  Bioactive compounds from marine actinomycetes.

Authors:  Renu Solanki; Monisha Khanna; Rup Lal
Journal:  Indian J Microbiol       Date:  2009-01-08       Impact factor: 2.461

Review 5.  Astonishing diversity of natural surfactants: 2. Polyether glycosidic ionophores and macrocyclic glycosides.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2005-03       Impact factor: 1.880

6.  Broadened glycosylation patterning of heterologously produced erythromycin.

Authors:  Lei Fang; Guojian Zhang; Omar El-Halfawy; Max Simon; Eric D Brown; Blaine A Pfeifer
Journal:  Biotechnol Bioeng       Date:  2018-09-15       Impact factor: 4.530

7.  Accelerating the discovery of biologically active small molecules using a high-throughput yeast halo assay.

Authors:  Nadine C Gassner; Craig M Tamble; Jonathan E Bock; Naomi Cotton; Kimberly N White; Karen Tenney; Robert P St Onge; Michael J Proctor; Guri Giaever; Corey Nislow; Ronald W Davis; Phillip Crews; Theodore R Holman; R Scott Lokey
Journal:  J Nat Prod       Date:  2007-02-10       Impact factor: 4.050

8.  Crystallization and preliminary X-ray analysis of vicenisaminyltransferase VinC.

Authors:  Eriko Nango; Atsushi Minami; Takashi Kumasaka; Tadashi Eguchi
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2008-05-24

9.  The crystal structure of the adenylation enzyme VinN reveals a unique β-amino acid recognition mechanism.

Authors:  Akimasa Miyanaga; Jolanta Cieślak; Yuji Shinohara; Fumitaka Kudo; Tadashi Eguchi
Journal:  J Biol Chem       Date:  2014-09-22       Impact factor: 5.157

10.  Cooperative Involvement of Glycosyltransferases in the Transfer of Amino Sugars during the Biosynthesis of the Macrolactam Sipanmycin by Streptomyces sp. Strain CS149.

Authors:  Mónica G Malmierca; Ignacio Pérez-Victoria; Jesús Martín; Fernando Reyes; Carmen Méndez; Carlos Olano; José A Salas
Journal:  Appl Environ Microbiol       Date:  2018-08-31       Impact factor: 4.792
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