Literature DB >> 8360098

Tetrafibricin, a novel fibrinogen receptor antagonist. II. Structural elucidation.

T Kamiyama1, Y Itezono, T Umino, T Satoh, N Nakayama, K Yokose.   

Abstract

The structure of tetrafibricin, a novel and potent fibrinogen receptor antagonist isolated from the culture broth of Streptomyces neyagawaensis NR0577, was determined. Tetrafibricin has a unique structure containing primary amine, conjugated tetraenoic acid, and polyhydroxy functionalities that is biosynthetically related to the polyene macrolide antibiotics.

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Year:  1993        PMID: 8360098     DOI: 10.7164/antibiotics.46.1047

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  7 in total

1.  Stereoselective synthesis of the C(1)-C(19) fragment of tetrafibricin.

Authors:  Ricardo Lira; William R Roush
Journal:  Org Lett       Date:  2007-02-01       Impact factor: 6.005

2.  Fluorous Mixture Synthesis of Four Stereoisomers of the C21-C40 Fragment of Tetrafibricin.

Authors:  Kai Zhang; Dennis P Curran
Journal:  Synlett       Date:  2010-03-01       Impact factor: 2.454

3.  Synthesis of C1-C20 and C21-C40 fragments of tetrafibricin.

Authors:  Venugopal Gudipati; Dennis P Curran
Journal:  Tetrahedron Lett       Date:  2011-04-27       Impact factor: 2.415

4.  SULFANYLATION OF 1,3-DITHIANE ANIONS BY 5-(ALKYLSULFANYL)-1-PHENYLTETRAZOLES.

Authors:  Venugopal Gudipati; Reena Bajpai; Dennis P Curran
Journal:  Collect Czechoslov Chem Commun       Date:  2009-06-01

5.  C(21)-C(40) of tetrafibricin via metal catalysis: beyond stoichiometric chiral reagents, auxiliaries, and premetalated nucleophiles.

Authors:  Esa T T Kumpulainen; Byungsoo Kang; Michael J Krische
Journal:  Org Lett       Date:  2011-04-06       Impact factor: 6.005

6.  Enantio- and diastereoselective synthesis of N-acetyl dihydrotetrafibricin methyl ester.

Authors:  Philippe Nuhant; William R Roush
Journal:  J Am Chem Soc       Date:  2013-03-26       Impact factor: 15.419

7.  Asymmetric alcohol C-H allylation and syn-crotylation: C9-C20 of tetrafibricin.

Authors:  Takahiko Itoh; T Patrick Montgomery; Antonio Recio; Michael J Krische
Journal:  Org Lett       Date:  2014-01-14       Impact factor: 6.005

  7 in total

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