Literature DB >> 8359830

Anticholestatic effect of picroliv, active hepatoprotective principle of Picrorhiza kurrooa, against carbon tetrachloride induced cholestasis.

B Saraswat1, P K Visen, G K Patnaik, B N Dhawan.   

Abstract

Picroliv showed a dose (3-12 mg/kg, po for 7 days) dependent choleretic activity as evidenced by increase in bile flow and its contents (bile salts and bile acids). Significant anticholestatic activity was also observed against carbon tetrachloride induced cholestasis in conscious rat, anaesthetized guinea pig and cat. Picroliv was more active than the known hepatoprotective drug silymarin.

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Year:  1993        PMID: 8359830

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN: 0019-5189            Impact factor:   0.818


  8 in total

1.  Evaluation of the Hepato and Nephron-Protective Effect of a Polyherbal Mixture using Wistar Albino Rats.

Authors:  Onyekachi Ogbonnaya Iroanya; Olumide Adedapo Adebesin; Joy Okpuzor
Journal:  J Clin Diagn Res       Date:  2014-06-20

2.  Hepatoprotective properties of aqueous leaf extract of Persea Americana, Mill (Lauraceae) 'avocado' against CCL4-induced damage in rats.

Authors:  Bartholomew I C Brai; Rahmat A Adisa; Adebimpe A Odetola
Journal:  Afr J Tradit Complement Altern Med       Date:  2014-01-28

3.  Two light responsive WRKY genes exhibit positive and negative correlation with picroside content in Picrorhiza kurrooa Royle ex Benth, an endangered medicinal herb.

Authors:  Tanvi Sharma; Tabasum Kawoosa; Parul Gahlan; Damini Sharma; Anish Kaachra; Vipin Hallan; Sanjay Kumar
Journal:  3 Biotech       Date:  2020-05-16       Impact factor: 2.406

4.  Evaluation of the antioxidant effects of Ziziphus mauritiana Lam. Leaf extracts against chronic ethanol-induced hepatotoxicity in rat liver.

Authors:  D Dahiru; O Obidoa
Journal:  Afr J Tradit Complement Altern Med       Date:  2007-10-27

5.  Evaluation of acute toxicity and hepatoprotective activity of the methanolic extract of Dichrostachys cinerea (Wight and Arn.) leaves.

Authors:  P Suresh Babu; V Krishna; K R Maruthi; K Shankarmurthy; Ramesh K Babu
Journal:  Pharmacognosy Res       Date:  2011-01

6.  Hepatoprotective Activity of the Ethanolic Extract of Ficus caricaLinn. LeavesinCarbon Tetrachloride-Induced Hepatotoxicityin Rats.

Authors:  Mohd Mujeeb; Shah Alam Khan; Vidhu Aeri; Babar Ali
Journal:  Iran J Pharm Res       Date:  2011       Impact factor: 1.696

7.  Evaluation of Hepatoprotective activity of Eriocaulon quinquangulare in vitro using porcine liver slices against ethanol induced liver toxicity and free radical scavenging capacity.

Authors:  Chamira Dilanka Fernando; Preethi Soysa
Journal:  BMC Complement Altern Med       Date:  2016-02-24       Impact factor: 3.659

8.  Antioxidant and Hepatoprotective Activity of a New Tablets Formulation from Tamarindus indica L.

Authors:  Jesús Rafael Rodriguez Amado; Ariadna Lafourcade Prada; Julio Cesar Escalona Arranz; Renato Pérez Rosés; Humberto Morris Quevedo; Hady Keita; Edgar Puente Zapata; Caio Pinho Fernandes; José Carlos Tavares Carvalho
Journal:  Evid Based Complement Alternat Med       Date:  2016-04-07       Impact factor: 2.629

  8 in total

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