Literature DB >> 8359466

Ficin: a cysteine proteinase with binding site-catalytic site signalling characteristics intermediate between those of papain and actinidin.

M Patel1, M P Thomas, I S Kayani, G W Mellor, E W Thomas, K Brocklehurst.   

Abstract

Mesh：

Substances：

Year:  1993        PMID： 8359466     DOI： 10.1042/bst021216s

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


× No keyword cloud information.
  3 in total

1.  Variation in aspects of cysteine proteinase catalytic mechanism deduced by spectroscopic observation of dithioester intermediates, kinetic analysis and molecular dynamics simulations.

Authors:  J D Reid; S Hussain; S K Sreedharan; T S Bailey; S Pinitglang; E W Thomas; C S Verma; K Brocklehurst
Journal:  Biochem J       Date:  2001-07-15       Impact factor: 3.857

2.  Ionization characteristics and chemical influences of aspartic acid residue 158 of papain and caricain determined by structure-related kinetic and computational techniques: multiple electrostatic modulators of active-centre chemistry.

Authors:  M A Noble; S Gul; C S Verma; K Brocklehurst
Journal:  Biochem J       Date:  2000-11-01       Impact factor: 3.857

3.  Structure of chymopapain M the late-eluted chymopapain deduced by comparative modelling techniques and active-centre characteristics determined by pH-dependent kinetics of catalysis and reactions with time-dependent inhibitors: the Cys-25/His-159 ion-pair is insufficient for catalytic competence in both chymopapain M and papain.

Authors:  M P Thomas; C M Topham; D Kowlessur; G W Mellor; E W Thomas; D Whitford; K Brocklehurst
Journal:  Biochem J       Date:  1994-06-15       Impact factor: 3.857
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.