Literature DB >> 8358434

3,400 new expressed sequence tags identify diversity of transcripts in human brain.

M D Adams1, A R Kerlavage, C Fields, J C Venter.   

Abstract

We present the results of the partial sequencing of over 3,400 expressed sequence tags (ESTs) from human brain cDNA clones, which increases the number of distinct genes expressed in the brain, that are represented by ESTs, to about 6,000. By choosing clones in an unbiased manner, it is possible to construct a profile of the transcriptional activity of the brain at different stages. Proteins that comprise the cytoskeleton are the most abundant; however, a large variety of regulatory proteins are also seen. About half of the ESTs predicted to contain a protein-coding region have no matches in the public peptide databases and may represent new gene families.

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Year:  1993        PMID： 8358434     DOI： 10.1038/ng0793-256

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  75 in total

Review 1.  Molecular profiling of clinical tissues specimens: feasibility and applications.

Authors:  M R Emmert-Buck; R L Strausberg; D B Krizman; M F Bonaldo; R F Bonner; D G Bostwick; M R Brown; K H Buetow; R F Chuaqui; K A Cole; P H Duray; C R Englert; J W Gillespie; S Greenhut; L Grouse; L W Hillier; K S Katz; R D Klausner; V Kuznetzov; A E Lash; G Lennon; W M Linehan; L A Liotta; M A Marra; P J Munson; D K Ornstein; V V Prabhu; C Prang; G D Schuler; M B Soares; C M Tolstoshev; C D Vocke; R H Waterston
Journal:  J Mol Diagn       Date:  2000-05       Impact factor: 5.568

Review 2.  Molecular profiling of clinical tissue specimens: feasibility and applications.

Authors:  M R Emmert-Buck; R L Strausberg; D B Krizman; M F Bonaldo; R F Bonner; D G Bostwick; M R Brown; K H Buetow; R F Chuaqui; K A Cole; P H Duray; C R Englert; J W Gillespie; S Greenhut; L Grouse; L W Hillier; K S Katz; R D Klausner; V Kuznetzov; A E Lash; G Lennon; W M Linehan; L A Liotta; M A Marra; P J Munson; D K Ornstein; V V Prabhu; C Prange; G D Schuler; M B Soares; C M Tolstoshev; C D Vocke; R H Waterston
Journal:  Am J Pathol       Date:  2000-04       Impact factor: 4.307

3.  Distinct roles of two conserved Staufen domains in oskar mRNA localization and translation.

Authors:  D R Micklem; J Adams; S Grünert; D St Johnston
Journal:  EMBO J       Date:  2000-03-15       Impact factor: 11.598

4.  BodyMap: a collection of 3' ESTs for analysis of human gene expression information.

Authors:  S Kawamoto; J Yoshii; K Mizuno; K Ito; Y Miyamoto; T Ohnishi; R Matoba; N Hori; Y Matsumoto; T Okumura; Y Nakao; H Yoshii; J Arimoto; H Ohashi; H Nakanishi; I Ohno; J Hashimoto; K Shimizu; K Maeda; H Kuriyama; K Nishida; A Shimizu-Matsumoto; W Adachi; R Ito; S Kawasaki; K S Chae
Journal:  Genome Res       Date:  2000-11       Impact factor: 9.043

5.  Oligo(dT) primer generates a high frequency of truncated cDNAs through internal poly(A) priming during reverse transcription.

Authors:  Douglas Kyung Nam; Sanggyu Lee; Guolin Zhou; Xiaohong Cao; Clarence Wang; Terry Clark; Jianjun Chen; Janet D Rowley; San Ming Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-23       Impact factor: 11.205

6.  Identification of calcium- and nitric oxide-regulated genes by differential analysis of library expression (DAzLE).

Authors:  Huiwu Li; Xiujing Gu; Valina L Dawson; Ted M Dawson
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-30       Impact factor: 11.205

7.  The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development.

Authors:  J D Alvarez; D H Yasui; H Niida; T Joh; D Y Loh; T Kohwi-Shigematsu
Journal:  Genes Dev       Date:  2000-03-01       Impact factor: 11.361

8.  A transcript finishing initiative for closing gaps in the human transcriptome.

Authors:  Mari Cleide Sogayar; Anamaria A Camargo; Fabiana Bettoni; Dirce Maria Carraro; Lilian C Pires; Raphael B Parmigiani; Elisa N Ferreira; Eloísa de Sá Moreira; Maria do Rosário D de O Latorre; Andrew J G Simpson; Luciana Oliveira Cruz; Theri Leica Degaki; Fernanda Festa; Katlin B Massirer; Mari C Sogayar; Fernando Camargo Filho; Luiz Paulo Camargo; Marco A V Cunha; Sandro J De Souza; Milton Faria; Silvana Giuliatti; Leonardo Kopp; Paulo S L de Oliveira; Paulo B Paiva; Anderson A Pereira; Daniel G Pinheiro; Renato D Puga; Jorge Estefano S de Souza; Dulcineia M Albuquerque; Luís E C Andrade; Gilson S Baia; Marcelo R S Briones; Ana M S Cavaleiro-Luna; Janete M Cerutti; Fernando F Costa; Eugenia Costanzi-Strauss; Enilza M Espreafico; Adriana C Ferrasi; Emer S Ferro; Maria A H Z Fortes; Joelma R F Furchi; Daniel Giannella-Neto; Gustavo H Goldman; Maria H S Goldman; Arthur Gruber; Gustavo S Guimarães; Christine Hackel; Flavio Henrique-Silva; Edna T Kimura; Suzana G Leoni; Cláudia Macedo; Bettina Malnic; Carina V Manzini B; Suely K N Marie; Nilce M Martinez-Rossi; Marcelo Menossi; Elisabete C Miracca; Maria A Nagai; Francisco G Nobrega; Marina P Nobrega; Sueli M Oba-Shinjo; Márika K Oliveira; Guilherme M Orabona; Audrey Y Otsuka; Maria L Paço-Larson; Beatriz M C Paixão; Jose R C Pandolfi; Maria I M C Pardini; Maria R Passos Bueno; Geraldo A S Passos; Joao B Pesquero; Juliana G Pessoa; Paula Rahal; Cláudia A Rainho; Caroline P Reis; Tatiana I Ricca; Vanderlei Rodrigues; Silvia R Rogatto; Camila M Romano; Janaína G Romeiro; Antonio Rossi; Renata G Sá; Magaly M Sales; Simone C Sant'Anna; Patrícia L Santarosa; Fernando Segato; Wilson A Silva; Ismael D C G Silva; Neusa P Silva; Andrea Soares-Costa; Maria F Sonati; Bryan E Strauss; Eloiza H Tajara; Sandro R Valentini; Fabiola E Villanova; Laura S Ward; Dalila L Zanette
Journal:  Genome Res       Date:  2004-06-14       Impact factor: 9.043

Review 9.  A review of the major penaeid shrimp EST studies and the construction of a shrimp transcriptome database based on the ESTs from four penaeid shrimp.

Authors:  Jiann-Horng Leu; Shu-Hwa Chen; Yu-Bin Wang; Yen-Chen Chen; Sheng-Yao Su; Chung-Yen Lin; Jan-Ming Ho; Chu-Fang Lo
Journal:  Mar Biotechnol (NY)       Date:  2010-04-17       Impact factor: 3.619

10.  Targeted discovery of novel human exons by comparative genomics.

Authors:  Adam Siepel; Mark Diekhans; Brona Brejová; Laura Langton; Michael Stevens; Charles L G Comstock; Colleen Davis; Brent Ewing; Shelly Oommen; Christopher Lau; Hung-Chun Yu; Jianfeng Li; Bruce A Roe; Phil Green; Daniela S Gerhard; Gary Temple; David Haussler; Michael R Brent
Journal:  Genome Res       Date:  2007-11-07       Impact factor: 9.043
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