Literature DB >> 8358224

Chemoenzymatic galactosialylation with integrated cofactor regeneration.

P Stangier1, W Treder, J Thiem.   

Abstract

As a precursor for the chemical synthesis of sialylated oligosaccharides, the trisaccharide glycoside Neu5Ac alpha (2-8)Gal beta (1-4)GlcNAc beta (1-O)-pent-4-ene was synthesized starting from GlcNAc beta (1-O)-pent-4-ene, UDP-glucose and N-acetylneuraminic acid in a one pot reaction employing galactosyltransferase and alpha (2-6)sialyltransferase in a complete cofactor regeneration system.

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Year:  1993        PMID： 8358224     DOI： 10.1007/bf00731183

Source DB:  PubMed          Journal:  Glycoconj J        ISSN： 0282-0080            Impact factor:   2.916


  10 in total

1.  Covalent coupling methods for inorganic support materials.

Authors:  H H Weetall
Journal:  Methods Enzymol       Date:  1976       Impact factor: 1.600

2.  Synthesis of a glycosidic affinity ligand for purification of cytidine-5'-monophosphosialate synthase.

Authors:  J Thiem; P Stangier; P Matschulat; H Paulsen
Journal:  Carbohydr Res       Date:  1992-02-17       Impact factor: 2.104

3.  Simple assay for sialyltransferase activity with a new fluorogenic substrate.

Authors:  T Sato; K Omichi; T Ikenaka
Journal:  J Biochem       Date:  1988-07       Impact factor: 3.387

Review 4.  Chemistry, metabolism, and biological functions of sialic acids.

Authors:  R Schauer
Journal:  Adv Carbohydr Chem Biochem       Date:  1982       Impact factor: 12.200

5.  Transfer of D-galactosyl groups to 6-O-substituted 2-acetamido-2-deoxy-D-glucose residues by use of bovine D-galactosyltransferase.

Authors:  M M Palcic; O P Srivastava; O Hindsgaul
Journal:  Carbohydr Res       Date:  1987-02-01       Impact factor: 2.104

6.  Sialylation of glycoprotein oligosaccharides with N-acetyl-, N-glycolyl-, and N-O-diacetylneuraminic acids.

Authors:  H H Higa; J C Paulson
Journal:  J Biol Chem       Date:  1985-07-25       Impact factor: 5.157

7.  Identification of a human neuroectodermal tumor antigen (OFA-I-2) as ganglioside GD2.

Authors:  L D Cahan; R F Irie; R Singh; A Cassidenti; J C Paulson
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

8.  Synthesis of a mucin-type O-glycosylated amino acid, beta-Gal-(1----3)-[alpha-Neu5Ac-(2----6)]-alpha-GalNAc-(1----3)- Ser.

Authors:  H Iijima; T Ogawa
Journal:  Carbohydr Res       Date:  1989-02-15       Impact factor: 2.104

9.  Purification of a sialyltransferase from bovine colostrum by affinity chromatography on CDP-agarose.

Authors:  J C Paulson; W E Beranek; R L Hill
Journal:  J Biol Chem       Date:  1977-04-10       Impact factor: 5.157

10.  The use of immobilised glycosyltransferases in the synthesis of sialyloligosaccharides.

Authors:  C Augé; R Fernandez-Fernandez; C Gautheron
Journal:  Carbohydr Res       Date:  1990-04-25       Impact factor: 2.104
  10 in total

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