Literature DB >> 8357603

Keratosis of the tympanic membrane and deep external auditory canal. A defect of auditory epithelial migration.

S Soucek1, L Michaels.   

Abstract

We have previously described the pathways of movement of epithelium on the tympanic membrane, showing that there are two discrete and separate zones. Four cases of keratosis of the tympanic membrane and deep external auditory canal are here reported. All patients complained of tinnitus and other aural symptoms. Sequences of otoscopic photography of daubs of dye placed on the tympanic membrane showed an abnormal anterior movement over the whole tympanic membrane in two cases and complete paralysis of movement in the two others. These findings suggest that the disorder arises from damage to basal epidermal cells caused by inflammation, which is probably due to infection. Treatment is by suction-stripping of keratin from the eardrum. Careful examination of the eardrum under magnification is required in all cases of tinnitus so as to detect this condition.

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Year:  1993        PMID: 8357603     DOI: 10.1007/bf00171698

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  7 in total

1.  EPITHELIAL MIGRATION ON THE TYMPANIC MEMBRANE.

Authors:  P W ALBERTI
Journal:  J Laryngol Otol       Date:  1964-09       Impact factor: 1.469

2.  Auditory epithelial migration on the human tympanic membrane: II. The existence of two discrete migratory pathways and their embryologic correlates.

Authors:  L Michaels; S Soucek
Journal:  Am J Anat       Date:  1990-11

3.  Stratified squamous epithelium in relation to the tympanic membrane: its development and kinetics.

Authors:  L Michaels; S Soucek
Journal:  Int J Pediatr Otorhinolaryngol       Date:  1991-09       Impact factor: 1.675

4.  The mechanism of ceruminolysis.

Authors:  A C Robinson; M Hawke; A MacKay; J K Ekem; M Stratis
Journal:  J Otolaryngol       Date:  1989-10

5.  Impacted cerumen: a disorder of keratinocyte separation in the superficial external ear canal?

Authors:  A C Robinson; M Hawke; J Naiberg
Journal:  J Otolaryngol       Date:  1990-04

6.  Keratosis obturans and external auditory canal cholesteatoma.

Authors:  M C Piepergerdes; B M Kramer; E E Behnke
Journal:  Laryngoscope       Date:  1980-03       Impact factor: 3.325

7.  Epithelial migration on the tympanic membrane and external canal.

Authors:  K Makino; M Amatsu
Journal:  Arch Otorhinolaryngol       Date:  1986
  7 in total
  1 in total

1.  A Hierarchy of Proliferative and Migratory Keratinocytes Maintains the Tympanic Membrane.

Authors:  Stacey M Frumm; Shengyang Kevin Yu; Joseph Chang; Jordan A Artichoker; Sonia M Scaria; Katharine P Lee; Lauren E Byrnes; Julie B Sneddon; Aaron D Tward
Journal:  Cell Stem Cell       Date:  2020-11-11       Impact factor: 25.269

  1 in total

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