A burn patient resuscitation therapy designed by computer simulation (BET). Part 2: Initial clinical validation.

The clinical results obtained from the first 40 burned patients resuscitated with 220 ml/h x BBSA (m2) of human serum albumin with concentrations of 10, 7.5, 5 and 2.5 per cent in lactated Ringer's (0-8, 8-16, 16-24 and 24-40 h post injury respectively), which we have called BET fluid therapy, were compared with those obtained in 58 patients resuscitated with lactated Ringer's 4 ml/kg of body weight/%BBSA during the first 24 h after burning. The results confirm the effectiveness of the BET form of fluid therapy during the shock phase after burning. The BET fluid therapy method differs from other procedures because of its lower volume of infused resuscitation solution with the rapid infusion of large amounts of colloid. These preliminary results have encouraged us to continue analysing this new method of fluid therapy.