Literature DB >> 835530

Acute copper intoxication. Pathophysiology and therapy with a case report.

F M Walsh, F J Crosson, M Bayley, J McReynolds, B J Pearson.   

Abstract

We report a case of cupric sulfate intoxication in a child who had a serum copper level of 1,650 mug/100 ml. His course was accompanied by hemolytic anemia and renal tubular damage. We review the pathophysiology of copper metabolism and intoxication. We also review modes of therapy, with specific reference to the initial approach, using dimercaprol (BAL) and edetic acid rather than penicillamine.

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Year:  1977        PMID: 835530     DOI: 10.1001/archpedi.1977.02120150031005

Source DB:  PubMed          Journal:  Am J Dis Child        ISSN: 0002-922X


  2 in total

1.  [Acute fatal copper intoxication. Casuistic and considerations on differential diagnosis (author's transl)].

Authors:  A Zober; M Geldmacher-von Mallinckrodt; B Schellmann
Journal:  Arch Toxicol       Date:  1978-08-09       Impact factor: 5.153

2.  Effects of cupric chloride on coagulation in human plasma: role of fibrinogen.

Authors:  Vance G Nielsen; Timothy D Ward; Paul M Ford
Journal:  J Thromb Thrombolysis       Date:  2018-10       Impact factor: 2.300

  2 in total

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