Literature DB >> 8353427

Gene therapy: adenovirus vectors.

K F Kozarsky1, J M Wilson.   

Abstract

The past year has seen a proliferation in the use of recombinant, replication-defective adenoviruses for experimental models of gene therapy. The fact that adenovirus infects most cell types with no requirement for cell division, combined with the high titers and high efficiency of gene transfer obtainable with recombinant adenovirus, make it a promising system for in vivo human gene therapy.

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Year:  1993        PMID： 8353427     DOI： 10.1016/0959-437x(93)90126-a

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  70 in total

Review 1.  Recent advances in molecular biological techniques and their relevance to pulmonary research.

Authors:  B W Robinson; D J Erle; D A Jones; S Shapiro; W J Metzger; S M Albelda; W C Parks; A Boylan
Journal:  Thorax       Date:  2000-04       Impact factor: 9.139

2.  Gene transfer and expression of platelet-derived growth factors modulate periodontal cellular activity.

Authors:  Z Zhu; C S Lee; K M Tejeda; W V Giannobile
Journal:  J Dent Res       Date:  2001-03       Impact factor: 6.116

3.  Prevalence of neutralizing antibodies to adenoviral serotypes 5 and 35 in the adult populations of The Gambia, South Africa, and the United States.

Authors:  Edward Nwanegbo; Eftyhia Vardas; Wentao Gao; Hilton Whittle; Huijie Sun; David Rowe; Paul D Robbins; Andrea Gambotto
Journal:  Clin Diagn Lab Immunol       Date:  2004-03

4.  Adenovirus vector pseudotyping in fiber-expressing cell lines: improved transduction of Epstein-Barr virus-transformed B cells.

Authors:  D J Von Seggern; S Huang; S K Fleck; S C Stevenson; G R Nemerow
Journal:  J Virol       Date:  2000-01       Impact factor: 5.103

5.  An adenoviral vaccine encoding full-length inactivated human Her2 exhibits potent immunogenicty and enhanced therapeutic efficacy without oncogenicity.

Authors:  Zachary C Hartman; Junping Wei; Takuya Osada; Oliver Glass; Gangjun Lei; Xiao-Yi Yang; Sharon Peplinski; Dong-Wan Kim; Wenle Xia; Neil Spector; Jeffrey Marks; William Barry; Amy Hobeika; Gayathri Devi; Andrea Amalfitano; Michael A Morse; H Kim Lyerly; Timothy M Clay
Journal:  Clin Cancer Res       Date:  2010-02-23       Impact factor: 12.531

6.  Persistence of recombinant adenovirus in vivo is not dependent on vector DNA replication.

Authors:  J E Nelson; M A Kay
Journal:  J Virol       Date:  1997-11       Impact factor: 5.103

7.  Nanoporous crystals of chicken embryo lethal orphan (CELO) adenovirus major coat protein, hexon.

Authors:  Lan Xu; Stacy D Benson; Roger M Burnett
Journal:  J Struct Biol       Date:  2006-09-14       Impact factor: 2.867

8.  Liver-directed gene transfer and prolonged expression of three major human ApoE isoforms in ApoE-deficient mice.

Authors:  K Tsukamoto; P Smith; J M Glick; D J Rader
Journal:  J Clin Invest       Date:  1997-07-01       Impact factor: 14.808

9.  Phenotype correction in retinal pigment epithelium in murine mucopolysaccharidosis VII by adenovirus-mediated gene transfer.

Authors:  T Li; B L Davidson
Journal:  Proc Natl Acad Sci U S A       Date:  1995-08-15       Impact factor: 11.205

10.  Treatment of experimental human mesothelioma using adenovirus transfer of the herpes simplex thymidine kinase gene.

Authors:  W R Smythe; H C Hwang; A A Elshami; K M Amin; S L Eck; B L Davidson; J M Wilson; L R Kaiser; S M Albelda
Journal:  Ann Surg       Date:  1995-07       Impact factor: 12.969
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