Literature DB >> 8352816

Characterisation of the central nervous depressant activity of a commercially available valerian root extract.

J Leuschner1, J Müller, M Rudmann.   

Abstract

The evaluation of a commercially available valerian root extract (Valdispert) revealed pronounced sedative properties in the mouse with respect to a reduction in motility and an increase in the thiopental sleeping-time. A direct comparison with diazepam and chlorpromazine revealed a moderate sedative activity for the tested extract. The extract showed only weak anticonvulsive properties.

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Year:  1993        PMID： 8352816

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN： 0004-4172


  9 in total

Review 1.  Drug interactions between herbal and prescription medicines.

Authors:  Elizabeth M Williamson
Journal:  Drug Saf       Date:  2003       Impact factor: 5.606

2.  Herbal Medicine: Is it an Alternative or an Unknown? A Brief Review of Popular Herbals Used by Patients in a Pain and Symptom Management Practice Setting.

Authors: 
Journal:  Curr Rev Pain       Date:  1999

Review 3.  The globalization of traditional medicine in northern peru: from shamanism to molecules.

Authors:  Rainer W Bussmann
Journal:  Evid Based Complement Alternat Med       Date:  2013-12-28       Impact factor: 2.629

4.  Valeriana officinalis Extracts Ameliorate Neuronal Damage by Suppressing Lipid Peroxidation in the Gerbil Hippocampus Following Transient Cerebral Ischemia.

Authors:  Dae Young Yoo; Hyo Young Jung; Sung Min Nam; Jong Whi Kim; Jung Hoon Choi; Youn-Gil Kwak; Miyoung Yoo; Sanghee Lee; Yeo Sung Yoon; In Koo Hwang
Journal:  J Med Food       Date:  2015-03-18       Impact factor: 2.786

5.  Effects of Valeriana officinalis extracts on [3H]flunitrazepam binding, synaptosomal [3H]GABA uptake, and hippocampal [3H]GABA release.

Authors:  J G Ortiz; J Nieves-Natal; P Chavez
Journal:  Neurochem Res       Date:  1999-11       Impact factor: 3.996

6.  Aqueous and Ethanolic Valeriana officinalis Extracts Change the Binding of Ligands to Glutamate Receptors.

Authors:  Lisa M Del Valle-Mojica; José M Cordero-Hernández; Giselle González-Medina; Igmeris Ramos-Vélez; Nairimer Berríos-Cartagena; Bianca A Torres-Hernández; José G Ortíz
Journal:  Evid Based Complement Alternat Med       Date:  2010-12-02       Impact factor: 2.629

7.  Selective Interactions of Valeriana officinalis Extracts and Valerenic Acid with [H]Glutamate Binding to Rat Synaptic Membranes.

Authors:  Lisa M Del Valle-Mojica; Yoshira M Ayala-Marín; Carmen M Ortiz-Sanchez; Bianca A Torres-Hernández; Safa Abdalla-Mukhaimer; José G Ortiz
Journal:  Evid Based Complement Alternat Med       Date:  2011-04-26       Impact factor: 2.629

8.  Skeletal muscle relaxant effect of a standardized extract of Valeriana officinalis L. after acute administration in mice.

Authors:  Dorian Caudal; Isabelle Guinobert; Aude Lafoux; Valérie Bardot; César Cotte; Isabelle Ripoche; Pierre Chalard; Corinne Huchet
Journal:  J Tradit Complement Med       Date:  2017-10-12

9.  Commonly Used Dietary Supplements on Coagulation Function during Surgery.

Authors:  Chong-Zhi Wang; Jonathan Moss; Chun-Su Yuan
Journal:  Medicines (Basel)       Date:  2015-07-27
  9 in total

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