| Literature DB >> 8350093 |
G G Harrigan1, A Ahmad, N Baj, T E Glass, A A Gunatilaka, D G Kingston.
Abstract
Bioassay-directed fractionation of the MeCOEt extract of Porella cordeana yielded drimenin [1] and aristolone [4], which were moderately toxic towards DNA-repair-deficient mutants of Saccharomyces cerevisiae. Three inactive sesquiterpenes, 7-ketoisodrimenin [2], 7-ketoisodrimenin-5-ene [3], and norpinguisanolide, were also obtained. Compounds 2 and 3 are new.Entities:
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Year: 1993 PMID： 8350093 DOI： 10.1021/np50096a016
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050