Literature DB >> 8347297

The tyrosine kinase connection: how GPI-anchored proteins activate T cells.

D Brown1.   

Abstract

How can crosslinking of cell-surface glycosylphosphatidylinositol-anchored proteins activate T cells when the proteins do not reach the cytosol? Recent results show that glycosylphosphatidylinositol-anchored proteins associate with tyrosine kinases of the src family. Kinase activity is stimulated when glycosylphosphatidylinositol-anchored proteins are crosslinked. How the proteins are linked across the membrane, however, remains an intriguing mystery.

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Year:  1993        PMID： 8347297     DOI： 10.1016/0952-7915(93)90052-t

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  46 in total

1.  Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion.

Authors:  A Davy; N W Gale; E W Murray; R A Klinghoffer; P Soriano; C Feuerstein; S M Robbins
Journal:  Genes Dev       Date:  1999-12-01       Impact factor: 11.361

Review 2.  Signaling through sphingolipid microdomains of the plasma membrane: the concept of signaling platform.

Authors:  D C Hoessli; S Ilangumaran; A Soltermann; P J Robinson; B Borisch
Journal:  Glycoconj J       Date:  2000 Mar-Apr       Impact factor: 2.916

3.  Surface antigen cross-linking triggers forced exit of a protozoan parasite from its host.

Authors:  T G Clark; T L Lin; H W Dickerson
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

4.  The association between glycosylphosphatidylinositol-anchored proteins and heterotrimeric G protein alpha subunits in lymphocytes.

Authors:  K R Solomon; C E Rudd; R W Finberg
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-11       Impact factor: 11.205

5.  HLA-G is found in lipid rafts and can act as a signaling molecule.

Authors:  Martina Comiskey; Kenneth E Domino; Carol M Warner
Journal:  Hum Immunol       Date:  2006-11-03       Impact factor: 2.850

6.  Active Lyn protein tyrosine kinase is selectively enriched within membrane microdomains of resting platelets.

Authors:  D J Dorahy; G F Burns
Journal:  Biochem J       Date:  1998-07-15       Impact factor: 3.857

7.  Determination of the non-ionic detergent insolubility and phosphoprotein associations of glycosylphosphatidylinositol-anchored proteins expressed on T cells.

Authors:  K R Solomon; M A Mallory; R W Finberg
Journal:  Biochem J       Date:  1998-09-01       Impact factor: 3.857

8.  Influence of MHC class I molecules on T-cell proliferation induced by CD3 or Thy-1 stimulation.

Authors:  N Amirayan; E Furrie; F Deleuil; A Mellor; L Leserman; P Machy
Journal:  Immunology       Date:  1995-09       Impact factor: 7.397

9.  Cholesterol-dependent retention of GPI-anchored proteins in endosomes.

Authors:  S Mayor; S Sabharanjak; F R Maxfield
Journal:  EMBO J       Date:  1998-08-17       Impact factor: 11.598

Review 10.  Mechanisms by which docosahexaenoic acid and related fatty acids reduce colon cancer risk and inflammatory disorders of the intestine.

Authors:  Robert S Chapkin; Jeongmin Seo; David N McMurray; Joanne R Lupton
Journal:  Chem Phys Lipids       Date:  2008-03-04       Impact factor: 3.329
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