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Literature DB >> 8346902

High-throughput microtiter plate-based chromogenic assays for glycosidase inhibitors.

Abstract

Rapid microtiter plate-based colorimetric assays have been developed that allow the screening of large numbers of samples for the presence of inhibitors of alpha-glucosidase, alpha-amylase, and beta-galactosidase. The assays are particularly useful for screening large numbers of microbial culture filtrates.

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Year: 1993 PMID： 8346902 DOI： 10.1007/bf02916417

Source DB: PubMed Journal: Appl Biochem Biotechnol ISSN： 0273-2289 Impact factor: 2.926

14 in total

1. Isoflavone rhamuniosides inhibitors of beta-galactosidase produced by actinomycetes.

Authors: T Aoyagi; T Hazato; M Kumagai; M Hamada; T Takeuchi
Journal: J Antibiot (Tokyo) Date: 1975-12 Impact factor: 2.649

2. Microalgae and cyanobacteria as a source of glycosidase inhibitors.

Authors: R J Cannell; S J Kellam; A M Owsianka; J M Walker
Journal: J Gen Microbiol Date: 1987-07

3. alpha-Glucosidase inhibitors. New complex oligosaccharides of microbial origin.

Authors: D D Schmidt; W Frommer; B Junge; L Müller; W Wingender; E Truscheit; D Schäfer
Journal: Naturwissenschaften Date: 1977-10

4. Purification and characterization of a sialidase inhibitor, siastatin, produced by Streptomyces.

Authors: H Umezawa; T Aoyagi; T Komiyama; H Morishima; M Hamada
Journal: J Antibiot (Tokyo) Date: 1974-12 Impact factor: 2.649

5. An enzyme inhibitor, panosialin, produced by Streptomyces. I. Biological activity, isolation and characterization of panosialin.

Authors: T Aoyagi; M Yagisawa; M Kumagai; M Hamada; Y Okami
Journal: J Antibiot (Tokyo) Date: 1971-12 Impact factor: 2.649

High-throughput microtiter plate-based chromogenic assays for glycosidase inhibitors.

1. Isoflavone rhamuniosides inhibitors of beta-galactosidase produced by actinomycetes.

2. Microalgae and cyanobacteria as a source of glycosidase inhibitors.

3. alpha-Glucosidase inhibitors. New complex oligosaccharides of microbial origin.

4. Purification and characterization of a sialidase inhibitor, siastatin, produced by Streptomyces.

5. An enzyme inhibitor, panosialin, produced by Streptomyces. I. Biological activity, isolation and characterization of panosialin.

6. Structure and synthesis of nojirimycin.

7. Effect of castanospermine on the structure and secretion of glycoprotein enzymes in Aspergillus fumigatus.

8. Effects of graded alpha-glucosidase inhibition on sugar absorption in vivo.

9. Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase.

10. A new approach to the treatment of nocturnal hypoglycemia using alpha-glucosidase inhibition.

1. A new resorufin-based alpha-glucosidase assay for high-throughput screening.