Literature DB >> 8346142

Invasive aspergillosis in two patients with acute lymphoblastic leukaemia in complete remission.

M L Turner1, L Russell, L J Milne, A C Parker.   

Abstract

Invasive aspergillosis is a disease of the immunosuppressed patient. We describe two patients with acute lymphoblastic leukaemia who attained complete remission, with partial or complete bone marrow recovery, but who went on to develop fatal invasive aspergillosis contemporaneous with recovery of neutrophil counts. Quantitative recovery of peripheral blood neutrophil counts does not guarantee control of Aspergillus infection, perhaps due to functional neutrophil deficiencies post-chemotherapy, and specific defensive strategies adopted by the organism itself.

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Year:  1993        PMID： 8346142      PMCID： PMC2399811          DOI： 10.1136/pgmj.69.811.405

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  12 in total

Review 1.  Antifungal and surgical treatment of invasive aspergillosis: review of 2,121 published cases.

Authors:  D W Denning; D A Stevens
Journal:  Rev Infect Dis       Date:  1990 Nov-Dec

Review 2.  Tissue destruction by neutrophils.

Authors:  S J Weiss
Journal:  N Engl J Med       Date:  1989-02-09       Impact factor: 91.245

3.  Phagocytic cell responses to Aspergillus fumigatus.

Authors:  M D Robertson; A Seaton; J A Raeburn
Journal:  FEMS Microbiol Immunol       Date:  1989-04

Review 4.  Aspergillosis.

Authors:  G P Bodey; S Vartivarian
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1989-05       Impact factor: 3.267

5.  Neutrophil function and pyogenic infections in bone marrow transplant recipients.

Authors:  W Zimmerli; A Zarth; A Gratwohl; B Speck
Journal:  Blood       Date:  1991-01-15       Impact factor: 22.113

6.  Invasive aspergillosis: clinical and pathological features of a new animal model.

Authors:  C L Spreadbury; T Krausz; S Pervez; J Cohen
Journal:  J Med Vet Mycol       Date:  1989

7.  Incidence of nosocomial aspergillosis in patients with leukemia over a twenty-year period.

Authors:  L L Klimowski; C Rotstein; K M Cummings
Journal:  Infect Control Hosp Epidemiol       Date:  1989-07       Impact factor: 3.254

8.  Experimental murine invasive pulmonary aspergillosis.

Authors:  D J Eisenstein; P W Biddinger; J C Rhodes
Journal:  Am J Clin Pathol       Date:  1990-04       Impact factor: 2.493

Review 9.  Fungal infections in the immunocompromised host.

Authors:  D K Stein; A M Sugar
Journal:  Diagn Microbiol Infect Dis       Date:  1989 Jul-Aug       Impact factor: 2.803

10.  Killing of Aspergillus fumigatus spores by human lung macrophages: a paradoxical effect of heat-labile serum components.

Authors:  M D Robertson; K M Kerr; A Seaton
Journal:  J Med Vet Mycol       Date:  1989
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