Literature DB >> 8344420

Molecular cloning and developmental expression of human cardiac troponin T.

L Mesnard1, F Samson, I Espinasse, J Durand, J Y Neveux, J J Mercadier.   

Abstract

We have isolated a full-size cDNA coding for cardiac troponin T (cTnT) from a human adult heart library, using a slow skeletal TnT probe. This cDNA detected a 1.2 kb mRNA in fetal and post-natal human heart, the amount of which increased during ontogenic development. Interestingly, a similar transcript was coexpressed in fetal skeletal muscle, together with the 0.9 kb slow skeletal muscle mRNA, and its expression was down-regulated during further development.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8344420     DOI： 10.1016/0014-5793(93)80981-y

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  5 in total

1.  A genomewide survey of developmentally relevant genes in Ciona intestinalis. IX. Genes for muscle structural proteins.

Authors:  Shota Chiba; Satoko Awazu; Machiko Itoh; Stephen T Chin-Bow; Nori Satoh; Yutaka Satou; Kenneth E M Hastings
Journal:  Dev Genes Evol       Date:  2003-05-10       Impact factor: 0.900

2.  Molecular polarity in tropomyosin-troponin T co-crystals.

Authors:  D Cabral-Lilly; L S Tobacman; J P Mehegan; C Cohen
Journal:  Biophys J       Date:  1997-10       Impact factor: 4.033

3.  A catalogue of genes in the cardiovascular system as identified by expressed sequence tags.

Authors:  C C Liew; D M Hwang; Y W Fung; C Laurenssen; E Cukerman; S Tsui; C Y Lee
Journal:  Proc Natl Acad Sci U S A       Date:  1994-10-25       Impact factor: 11.205

4.  Altered cardiac troponin T in vitro function in the presence of a mutation implicated in familial hypertrophic cardiomyopathy.

Authors:  D Lin; A Bobkova; E Homsher; L S Tobacman
Journal:  J Clin Invest       Date:  1996-06-15       Impact factor: 14.808

5.  Cardiac troponin T Arg92Trp mutation and progression from hypertrophic to dilated cardiomyopathy.

Authors:  N Fujino; M Shimizu; H Ino; K Okeie; M Yamaguchi; T Yasuda; H Kokado; H Mabuchi
Journal:  Clin Cardiol       Date:  2001-05       Impact factor: 2.882
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.