Literature DB >> 8341805

How tautological are interspecies correlations of carcinogenic potencies?

D A Freedman1, L S Gold, T H Slone.   

Abstract

Crouch and Wilson demonstrated a strong correlation between carcinogenic potencies in rats and mice, supporting the extrapolation from mouse to man. Bernstein et al., however, show that the observed correlation is mainly a statistical artifact of bioassay design. Crouch et al. have a comeback. This paper will review the arguments and present some new data. The correlation is largely (but not totally) tautological, confirming results in Bernstein et al.

Entities:  

Mesh：

Year:  1993        PMID： 8341805     DOI： 10.1111/j.1539-6924.1993.tb01078.x

Source DB:  PubMed          Journal:  Risk Anal        ISSN： 0272-4332            Impact factor:   4.000


  3 in total

Review 1.  Sixth plot of the carcinogenic potency database: results of animal bioassays published in the General Literature 1989 to 1990 and by the National Toxicology Program 1990 to 1993.

Authors:  L S Gold; N B Manley; T H Slone; G B Garfinkel; B N Ames; L Rohrbach; B R Stern; K Chow
Journal:  Environ Health Perspect       Date:  1995-11       Impact factor: 9.031

2.  Supplement to the Carcinogenic Potency Database (CPDB): results of animal bioassays published in the general literature in 1993 to 1994 and by the National Toxicology Program in 1995 to 1996.

Authors:  L S Gold; N B Manley; T H Slone; L Rohrbach
Journal:  Environ Health Perspect       Date:  1999-08       Impact factor: 9.031

3.  Biological networks for predicting chemical hepatocarcinogenicity using gene expression data from treated mice and relevance across human and rat species.

Authors:  Reuben Thomas; Russell S Thomas; Scott S Auerbach; Christopher J Portier
Journal:  PLoS One       Date:  2013-05-30       Impact factor: 3.240
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.