Literature DB >> 8340900

Cellular immune response to SIVmac and HIV-2 in macaques: model for the human HIV-1 infection.

G Voss1, G Hunsmann.   

Abstract

SIV and HIV-2 infection of macaques has become a widely used model to study human HIV infection because the pathogenicity of, as well as the immune responses to, the viruses can be examined conveniently. In particular, the cellular immune responses to SIV or HIV-2 have been investigated thoroughly. This review summarizes the knowledge about helper and cytotoxic T-cell immunity in macaques, and it discusses the relevance and applications of this primate animal model for AIDS research.

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Year:  1993        PMID： 8340900

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr (1988)        ISSN： 0894-9255


  3 in total

1.  Brucella abortus conjugated with a peptide derived from the V3 loop of human immunodeficiency virus (HIV) type 1 induces HIV-specific cytotoxic T-cell responses in normal and in CD4+ cell-depleted BALB/c mice.

Authors:  C Lapham; B Golding; J Inman; R Blackburn; J Manischewitz; P Highet; H Golding
Journal:  J Virol       Date:  1996-05       Impact factor: 5.103

2.  ENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids.

Authors:  L A Pinto; J Sullivan; J A Berzofsky; M Clerici; H A Kessler; A L Landay; G M Shearer
Journal:  J Clin Invest       Date:  1995-08       Impact factor: 14.808

3.  APOBEC3G polymorphism as a selective barrier to cross-species transmission and emergence of pathogenic SIV and AIDS in a primate host.

Authors:  Annabel Krupp; Kevin R McCarthy; Marcel Ooms; Michael Letko; Jennifer S Morgan; Viviana Simon; Welkin E Johnson
Journal:  PLoS Pathog       Date:  2013-10-03       Impact factor: 6.823
  3 in total

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