| Literature DB >> 8340536 |
Y Taniguchi1, T Sakamoto, M Shimizu.
Abstract
A 43-year-old woman had asymptomatic eruptions on the anterior sides of both legs for 5 years. Biopsy specimens revealed the typical findings of necrobiosis lipoidica. An immunofluorescence study demonstrated no deposits of immunoglobulins, complement, or fibrinogen in vessel walls. Immunohistochemical staining revealed CD4 positive lymphocytes dominating in the lesion and strong expression of ICAM-1 on the endothelial cells, giant cells, lymphocytes and dermal fibroblasts in the lesion. The eruptions resolved remarkably with oral corticosteroid therapy.Entities:
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Year: 1993 PMID： 8340536 DOI： 10.1111/j.1346-8138.1993.tb01396.x
Source DB: PubMed Journal: J Dermatol ISSN： 0385-2407 Impact factor: 4.005