Literature DB >> 833819

Synthesis and antiinflammatory activity of some 2-substituted 4- and 7-benzoxazoleacetic and alpha-methylacetic acids.

D Evans, C E Smith, W R Williamson.   

Abstract

4- and 7-benzoxazoleacetic and alpha-methylacetic acids substituted in the 2 position with phenyl and substituted phenyl groups have been synthesized and tested on the carrageenan-induced rat paw edema assay. The only compound found to have significant activity, albeit of a low order, was 2-phenyl-alpha-methyl-7-benzoxazoleacetic acid.

Entities:  

Mesh:

Substances:

Year:  1977        PMID: 833819     DOI: 10.1021/jm00211a039

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


  2 in total

1.  Construction of Escherichia coli strains for conversion of nitroacetophenones to ortho-aminophenols.

Authors:  Venkateswarlu Kadiyala; Lloyd J Nadeau; Jim C Spain
Journal:  Appl Environ Microbiol       Date:  2003-11       Impact factor: 4.792

2.  Oxidative dearomatization of phenols and anilines via lambda(3)- and lambda(5)-iodane-mediated phenylation and oxygenation.

Authors:  Stéphane Quideau; Laurent Pouységu; Aurélie Ozanne; Julien Gagnepain
Journal:  Molecules       Date:  2005-01-31       Impact factor: 4.411

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.