Literature DB >> 8336342

Toward a novel metal-based chemotherapy against tropical diseases. 1. Enhancement of the efficacy of clotrimazole against Trypanosoma cruzi by complexation to ruthenium in RuCl2(clotrimazole)2.

R A Sánchez-Delgado1, K Lazardi, L Rincón, J A Urbina.   

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Year:  1993        PMID: 8336342     DOI: 10.1021/jm00066a014

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  11 in total

1.  Spectroscopic Study of the Interactions of Ruthenium-Ketoconazole Complexes of Known Antiparasitic Activity with Human Serum Albumin and Apotransferrin.

Authors:  Jesús G Estrada; Roberto A Sánchez-Delgado
Journal:  J Mex Chem Soc       Date:  2013       Impact factor: 0.524

2.  Metal-drug synergy: new ruthenium(II) complexes of ketoconazole are highly active against Leishmania major and Trypanosoma cruzi and nontoxic to human or murine normal cells.

Authors:  Eva Iniguez; Antonio Sánchez; Miguel A Vasquez; Alberto Martínez; Joanna Olivas; Aaron Sattler; Roberto A Sánchez-Delgado; Rosa A Maldonado
Journal:  J Biol Inorg Chem       Date:  2013-07-24       Impact factor: 3.358

3.  Searching for new chemotherapies for tropical diseases: ruthenium-clotrimazole complexes display high in vitro activity against Leishmania major and Trypanosoma cruzi and low toxicity toward normal mammalian cells.

Authors:  Alberto Martínez; Teresia Carreon; Eva Iniguez; Atilio Anzellotti; Antonio Sánchez; Marina Tyan; Aaron Sattler; Linda Herrera; Rosa A Maldonado; Roberto A Sánchez-Delgado
Journal:  J Med Chem       Date:  2012-04-09       Impact factor: 7.446

4.  Interactions of arene-Ru(II)-chloroquine complexes of known antimalarial and antitumor activity with human serum albumin (HSA) and transferrin.

Authors:  Alberto Martínez; Javier Suárez; Tiffany Shand; Richard S Magliozzo; Roberto A Sánchez-Delgado
Journal:  J Inorg Biochem       Date:  2011-01       Impact factor: 4.155

5.  Arene-Ru(II)-chloroquine complexes interact with DNA, induce apoptosis on human lymphoid cell lines and display low toxicity to normal mammalian cells.

Authors:  Alberto Martínez; Chandima S K Rajapakse; Roberto A Sánchez-Delgado; Armando Varela-Ramirez; Carolina Lema; Renato J Aguilera
Journal:  J Inorg Biochem       Date:  2010-05-15       Impact factor: 4.155

6.  Synthesis, characterization, and in vitro antimalarial and antitumor activity of new ruthenium(II) complexes of chloroquine.

Authors:  Chandima S K Rajapakse; Alberto Martínez; Becky Naoulou; Andrzej A Jarzecki; Liliana Suárez; Christiane Deregnaucourt; Véronique Sinou; Joseph Schrével; Elgilda Musi; Grazia Ambrosini; Gary K Schwartz; Roberto A Sánchez-Delgado
Journal:  Inorg Chem       Date:  2009-02-02       Impact factor: 5.165

7.  The mechanism of antimalarial action of the ruthenium(II)-chloroquine complex [RuCl(2)(CQ)] (2).

Authors:  Alberto Martínez; Chandima S K Rajapakse; Becky Naoulou; Yasemin Kopkalli; Lesley Davenport; Roberto A Sánchez-Delgado
Journal:  J Biol Inorg Chem       Date:  2008-02-28       Impact factor: 3.358

8.  Metallocene antimalarials: the continuing quest.

Authors:  Margaret A L Blackie; Kelly Chibale
Journal:  Met Based Drugs       Date:  2008

9.  Synthesis and Spectroscopic and Biological Activities of Zn(II) Porphyrin with Oxygen Donors.

Authors:  Gauri Devi Bajju; Sujata Kundan; Madhulika Bhagat; Deepmala Gupta; Ashu Kapahi; Geeta Devi
Journal:  Bioinorg Chem Appl       Date:  2014-03-16       Impact factor: 7.778

10.  Microwave assisted synthesis, spectral and antifungal studies of 2-phenyl-N,N'-bis(pyridin-4-ylcarbonyl)butanediamide ligand and its metal complexes.

Authors:  Rayees Ahmad Shiekh; Maqsood Ahmad Malik; Shaeel Ahmed Al-Thabaiti; Mohmmad Younus Wani; Arshid Nabi
Journal:  ScientificWorldJournal       Date:  2014-03-19
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