| Literature DB >> 8335385 |
T G Sieck1, M A Moors, H R Buckley, K J Blank.
Abstract
The role of T lymphocytes in disseminated candidiasis in a mouse model of irradiation-induced immunosuppression was investigated. A continuously cultured Candida albicans-specific T-cell line mediated protection of sublethally irradiated mice from disseminated candidiasis as measured by both the fungal load in the kidneys and mortality. These results are the first to demonstrate directly a role for antigen-specific T cells in the protective immune response against murine disseminated candidiasis.Entities:
Mesh:
Year: 1993 PMID: 8335385 PMCID: PMC281036 DOI: 10.1128/iai.61.8.3540-3543.1993
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441