Literature DB >> 8335385

Protection against murine disseminated candidiasis mediated by a Candida albicans-specific T-cell line.

T G Sieck1, M A Moors, H R Buckley, K J Blank.   

Abstract

The role of T lymphocytes in disseminated candidiasis in a mouse model of irradiation-induced immunosuppression was investigated. A continuously cultured Candida albicans-specific T-cell line mediated protection of sublethally irradiated mice from disseminated candidiasis as measured by both the fungal load in the kidneys and mortality. These results are the first to demonstrate directly a role for antigen-specific T cells in the protective immune response against murine disseminated candidiasis.

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Year:  1993        PMID: 8335385      PMCID: PMC281036          DOI: 10.1128/iai.61.8.3540-3543.1993

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  28 in total

1.  Gastrointestinal candidiasis in a murine model of severe combined immunodeficiency syndrome.

Authors:  R Narayanan; W A Joyce; R A Greenfield
Journal:  Infect Immun       Date:  1991-06       Impact factor: 3.441

Review 2.  Candida infections in the intensive care unit.

Authors:  J D Sobel
Journal:  Crit Care Clin       Date:  1988-04       Impact factor: 3.598

Review 3.  Fungal infections in patients with AIDS and AIDS-related complex.

Authors:  K Holmberg; R D Meyer
Journal:  Scand J Infect Dis       Date:  1986

4.  Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator.

Authors:  R H Weisbart; D W Golde; S C Clark; G G Wong; J C Gasson
Journal:  Nature       Date:  1985 Mar 28-Apr 3       Impact factor: 49.962

5.  Role of CD4+ lymphocytes in resistance to mucosal candidiasis.

Authors:  M T Cantorna; E Balish
Journal:  Infect Immun       Date:  1991-07       Impact factor: 3.441

6.  Mucosal and systemic candidiasis in congenitally immunodeficient mice.

Authors:  M T Cantorna; E Balish
Journal:  Infect Immun       Date:  1990-04       Impact factor: 3.441

7.  Fungal infection in chronic granulomatous disease. The importance of the phagocyte in defense against fungi.

Authors:  M S Cohen; R E Isturiz; H L Malech; R K Root; C M Wilfert; L Gutman; R H Buckley
Journal:  Am J Med       Date:  1981-07       Impact factor: 4.965

8.  Experimental Candida albicans infection in conventional mice and germfree rats.

Authors:  T Rogers; E Balish
Journal:  Infect Immun       Date:  1976-07       Impact factor: 3.441

9.  Candidiasis in cancer patients.

Authors:  G P Bodey
Journal:  Am J Med       Date:  1984-10-30       Impact factor: 4.965

10.  Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection.

Authors:  R I Lehrer; M J Cline
Journal:  J Clin Invest       Date:  1969-08       Impact factor: 14.808

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  10 in total

1.  Increased susceptibility to Candida infection following cecal ligation and puncture.

Authors:  Christopher G Davis; Kathy Chang; Dale Osborne; Andrew H Walton; W Michael Dunne; Jared T Muenzer
Journal:  Biochem Biophys Res Commun       Date:  2011-09-12       Impact factor: 3.575

Review 2.  Th17 cells in immunity to Candida albicans.

Authors:  Nydiaris Hernández-Santos; Sarah L Gaffen
Journal:  Cell Host Microbe       Date:  2012-05-17       Impact factor: 21.023

3.  Antigenic properties and processing requirements of 65-kilodalton mannoprotein, a major antigen target of anti-Candida human T-cell response, as disclosed by specific human T-cell clones.

Authors:  R Nisini; G Romagnoli; M J Gomez; R La Valle; A Torosantucci; S Mariotti; R Teloni; A Cassone
Journal:  Infect Immun       Date:  2001-06       Impact factor: 3.441

4.  Gamma interferon is not essential in host defense against disseminated candidiasis in mice.

Authors:  Q Qian; J E Cutler
Journal:  Infect Immun       Date:  1997-05       Impact factor: 3.441

5.  Lack of effect of Candida albicans mannan on development of protective immune responses in experimental murine candidiasis.

Authors:  R E Garner; J E Domer
Journal:  Infect Immun       Date:  1994-02       Impact factor: 3.441

6.  Mice immunized by primary vaginal Candida albicans infection develop acquired vaginal mucosal immunity.

Authors:  P L Fidel; M E Lynch; D H Conaway; L Tait; J D Sobel
Journal:  Infect Immun       Date:  1995-02       Impact factor: 3.441

Review 7.  T helper cell dichotomy to Candida albicans: implications for pathology, therapy, and vaccine design.

Authors:  L Romani; E Cenci; A Menacci; F Bistoni; P Puccetti
Journal:  Immunol Res       Date:  1995       Impact factor: 2.829

Review 8.  Production and function of cytokines in natural and acquired immunity to Candida albicans infection.

Authors:  R B Ashman; J M Papadimitriou
Journal:  Microbiol Rev       Date:  1995-12

9.  Antibody response that protects against disseminated candidiasis.

Authors:  Y Han; J E Cutler
Journal:  Infect Immun       Date:  1995-07       Impact factor: 3.441

10.  Effectiveness of a vaccine composed of heat-killed Candida albicans and a novel mucosal adjuvant, LT(R192G), against systemic candidiasis.

Authors:  L Cárdenas-Freytag; E Cheng; P Mayeux; J E Domer; J D Clements
Journal:  Infect Immun       Date:  1999-02       Impact factor: 3.441

  10 in total

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