| Literature DB >> 8335384 |
Abstract
Poly(I . C) enhanced the susceptibility of CB-17 (BALB/c) mice to acute systemic candidiasis. Poly(I . C), supernatants from poly(I . C)-treated macrophages, or alpha and beta interferons suppressed macrophage candidacidal activity in vitro. Thus, poly(I . C)-induced interferons may enhance the susceptibility of CB-17 mice to candidiasis by suppressing macrophage candidacidal activity in an autocrine fashion.Entities:
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Year: 1993 PMID: 8335384 PMCID: PMC281033 DOI: 10.1128/iai.61.8.3530-3532.1993
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441