Literature DB >> 8334225

Close proximity of the genes for leukemia inhibitory factor and oncostatin M.

E Jeffery1, V Price, D P Gearing.   

Abstract

Leukemia inhibitory factor (LIF) and oncostatin M (OSM) are structurally related cytokines that share a common receptor complex. The genes for LIF and OSM have previously been reported to be on human chromosome 22. We report here the isolation of a single 73 kbp human genomic yeast artificial chromosome clone that contains the LIF and OSM genes. The two genes lie within 19 kbp of each other and are transcribed in opposite directions.

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Year:  1993        PMID： 8334225     DOI： 10.1016/1043-4666(93)90048-a

Source DB:  PubMed          Journal:  Cytokine        ISSN： 1043-4666            Impact factor:   3.861


  8 in total

1.  The AB loop and D-helix in binding site III of human Oncostatin M (OSM) are required for OSM receptor activation.

Authors:  Juan M Adrian-Segarra; Natalie Schindler; Praveen Gajawada; Holger Lörchner; Thomas Braun; Jochen Pöling
Journal:  J Biol Chem       Date:  2018-03-06       Impact factor: 5.157

2.  Specificity and function of monoclonal antibodies directed against Ewing sarcoma cells.

Authors:  L R Shi; D Eichelbauer; F Borchard; H Jürgens; U Göbel; E M Schneider
Journal:  Cancer Immunol Immunother       Date:  1994-03       Impact factor: 6.968

3.  A unique loop structure in oncostatin M determines binding affinity toward oncostatin M receptor and leukemia inhibitory factor receptor.

Authors:  Srinivas Chollangi; Timothy Mather; Karla K Rodgers; John D Ash
Journal:  J Biol Chem       Date:  2012-07-24       Impact factor: 5.157

4.  Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor.

Authors:  D P Gearing; S F Ziegler; M R Comeau; D Friend; B Thoma; D Cosman; L Park; B Mosley
Journal:  Proc Natl Acad Sci U S A       Date:  1994-02-01       Impact factor: 11.205

5.  Developmental abnormalities in mice transgenic for bovine oncostatin M.

Authors:  N Malik; H S Haugen; B Modrell; M Shoyab; C H Clegg
Journal:  Mol Cell Biol       Date:  1995-05       Impact factor: 4.272

6.  The AB loop of oncostatin M (OSM) determines species-specific signaling in humans and mice.

Authors:  Juan M Adrian-Segarra; Krishnamoorthy Sreenivasan; Praveen Gajawada; Holger Lörchner; Thomas Braun; Jochen Pöling
Journal:  J Biol Chem       Date:  2018-10-29       Impact factor: 5.157

7.  Characterization of the rat oncostatin M receptor complex which resembles the human, but differs from the murine cytokine receptor.

Authors:  Johannes Drechsler; Joachim Grötzinger; Heike M Hermanns
Journal:  PLoS One       Date:  2012-08-22       Impact factor: 3.240

8.  Evolutionary divergence and functions of the human interleukin (IL) gene family.

Authors:  Chad Brocker; David Thompson; Akiko Matsumoto; Daniel W Nebert; Vasilis Vasiliou
Journal:  Hum Genomics       Date:  2010-10       Impact factor: 4.639
  8 in total

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