Literature DB >> 8334162

The role of the beta-subunit of initiation factor eIF-2 in initiation complex formation.

A Flynn1, S Oldfield, C G Proud.   

Abstract

The functional properties of preparations of protein synthesis initiation factor eIF-2 which lack the beta-subunit (as confirmed immunologically) were compared with those of the heterotrimeric factor. The former can bind guanine nucleotides but not initiator tRNA, and also exhibits a substantially reduced rate of initiation factor eIF-2B-mediated GDP/GTP-exchange.

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Year:  1993        PMID： 8334162     DOI： 10.1016/0167-4781(93)90105-m

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  9 in total

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Review 4.  Molecular mechanisms for the control of translation by insulin.

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Journal:  EMBO J       Date:  2002-04-02       Impact factor: 11.598

6.  Ligand interactions with eukaryotic translation initiation factor 2: role of the gamma-subunit.

Authors:  F L Erickson; E M Hannig
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Review 7.  Human Cytomegalovirus Strategies to Maintain and Promote mRNA Translation.

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8.  Roles of yeast eIF2α and eIF2β subunits in the binding of the initiator methionyl-tRNA.

Authors:  Marie Naveau; Christine Lazennec-Schurdevin; Michel Panvert; Etienne Dubiez; Yves Mechulam; Emmanuelle Schmitt
Journal:  Nucleic Acids Res       Date:  2012-11-27       Impact factor: 16.971

9.  mTORC1 and CK2 coordinate ternary and eIF4F complex assembly.

Authors:  Valentina Gandin; Laia Masvidal; Marie Cargnello; Laszlo Gyenis; Shannon McLaughlan; Yutian Cai; Clara Tenkerian; Masahiro Morita; Preetika Balanathan; Olivier Jean-Jean; Vuk Stambolic; Matthias Trost; Luc Furic; Louise Larose; Antonis E Koromilas; Katsura Asano; David Litchfield; Ola Larsson; Ivan Topisirovic
Journal:  Nat Commun       Date:  2016-04-04       Impact factor: 14.919
  9 in total

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