Literature DB >> 8332647

Reduced total complement haemolytic activity in schizophrenic patients.

B Spivak1, M Radwan, J Brandon, Y Baruch, M Stawski, S Tyano, A Weizman.   

Abstract

Serum concentrations of the third and fourth components of the complement system and total complement haemolytic activity were measured in 167 psychiatric patients. Total complement haemolytic activity was decreased in chronic schizophrenic patients as compared to healthy controls and bipolar patients. The relatively diminished total haemolytic activity was not attributable to drug treatment. It is not clear if the reduced total haemolytic activity is an epiphenomenon or related to the involvement of an autoimmune process in the pathophysiology of schizophrenia.

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Year:  1993        PMID: 8332647     DOI: 10.1017/s0033291700028397

Source DB:  PubMed          Journal:  Psychol Med        ISSN: 0033-2917            Impact factor:   7.723


  7 in total

Review 1.  The complement system in schizophrenia.

Authors:  Karine R Mayilyan; Daniel R Weinberger; Robert B Sim
Journal:  Drug News Perspect       Date:  2008-05

Review 2.  The complement system in schizophrenia: where are we now and what's next?

Authors:  Julia J Woo; Jennie G Pouget; Clement C Zai; James L Kennedy
Journal:  Mol Psychiatry       Date:  2019-08-22       Impact factor: 15.992

Review 3.  Aberrant Complement System Activation in Neurological Disorders.

Authors:  Karolina Ziabska; Malgorzata Ziemka-Nalecz; Paulina Pawelec; Joanna Sypecka; Teresa Zalewska
Journal:  Int J Mol Sci       Date:  2021-04-28       Impact factor: 5.923

Review 4.  Neuro-Immune Hemostasis: Homeostasis and Diseases in the Central Nervous System.

Authors:  Ciro De Luca; Anna Maria Colangelo; Lilia Alberghina; Michele Papa
Journal:  Front Cell Neurosci       Date:  2018-11-26       Impact factor: 5.505

5.  Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

Authors:  Konasale M Prasad; Kodavali V Chowdari; Leonardo A D'Aiuto; Satish Iyengar; Jeffrey A Stanley; Vishwajit L Nimgaonkar
Journal:  Transl Psychiatry       Date:  2018-07-19       Impact factor: 6.222

Review 6.  Peripheral complement proteins in schizophrenia: A systematic review and meta-analysis of serological studies.

Authors:  David Mongan; Sophie Sabherwal; Subash Raj Susai; Melanie Föcking; Mary Cannon; David R Cotter
Journal:  Schizophr Res       Date:  2020-05-24       Impact factor: 4.939

Review 7.  The complement system: a gateway to gene-environment interactions in schizophrenia pathogenesis.

Authors:  V L Nimgaonkar; K M Prasad; K V Chowdari; E G Severance; R H Yolken
Journal:  Mol Psychiatry       Date:  2017-08-01       Impact factor: 15.992

  7 in total

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