Prolonged postsynaptic changes in the sensorimotor cortex of the awake rabbit in response to stimulation of fibers of the white matter of the new cortex and the corpus callosum.

The postsynaptic changes in the focal potentials of the sensorimotor cortex of the awake rabbit was investigated in this study following tetanization of the corpus callosum and the white matter. Stimulation of these structures was carried out during testing. A prolonged (hour-long) increase in the amplitude of the responses was observed in some of the experiments following tetanization, as compared with the control prior tetanization. Just as long a decrease in the amplitude of the responses tested developed in a number of experiments in the posttetanic period. It was concluded that prolonged plastic changes can occur in different directions in the sensorimotor cortex of the awake rabbit.