Massive ovarian edema in a woman receiving clomiphene citrate. A case report.

There have been 65 previously reported cases of massive ovarian edema. We present a case in a woman receiving clomiphene citrate. It is an uncommon, benign condition and usually involves the right ovary. Patients frequently present with intermittent abdominal pain, menstrual irregularities and occasional virilization. Incomplete ovarian torsion and edema formation secondary to a preexisting ovarian lesion are the postulated mechanisms. Our report is unusual because it is the first of massive ovarian edema in a woman receiving clomiphene citrate.