Literature DB >> 8330208

High-affinity nerve growth factor receptor (Trk) immunoreactivity is localized in cholinergic neurons of the basal forebrain and striatum in the adult rat brain.

T L Steininger1, B H Wainer, R Klein, M Barbacid, H C Palfrey.   

Abstract

Trk-immunoreactivity was observed in basal forebrain and striatal cholinergic neurons, whereas low-affinity NGF receptor immunoreactivity was observed in basal forebrain but not striatal cholinergic neurons. Since NGF exerts trophic actions on both basal forebrain and striatal cholinergic populations, the presence of Trk in these neurons lends strong support for an essential role of Trk in NGF-responsive neurons, but suggests that the low affinity receptor is not necessary for NGF actions in the striatum.

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Year:  1993        PMID： 8330208     DOI： 10.1016/0006-8993(93)91681-h

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  21 in total

1.  Ciliary neurotrophic factor protects striatal output neurons in an animal model of Huntington disease.

Authors:  K D Anderson; N Panayotatos; T L Corcoran; R M Lindsay; S J Wiegand
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-09       Impact factor: 11.205

2.  A role for TrkA during maturation of striatal and basal forebrain cholinergic neurons in vivo.

Authors:  A M Fagan; M Garber; M Barbacid; I Silos-Santiago; D M Holtzman
Journal:  J Neurosci       Date:  1997-10-15       Impact factor: 6.167

3.  Expression of NGF and NT3 mRNAs in hippocampal interneurons innervated by the GABAergic septohippocampal pathway.

Authors:  N Rocamora; M Pascual; L Acsàdy; L de Lecea; T F Freund; E Soriano
Journal:  J Neurosci       Date:  1996-06-15       Impact factor: 6.167

Review 4.  Experimental neurotrophic factor therapy leads to cortical synaptic remodeling and compensates for behavioral deficits.

Authors:  A C Cuello
Journal:  J Psychiatry Neurosci       Date:  1997-01       Impact factor: 6.186

Review 5.  Autoradiographical and immunohistochemical analysis of receptor localization in the central nervous system.

Authors:  J G Chabot; S Kar; R Quirion
Journal:  Histochem J       Date:  1996-11

6.  TrkA gene ablation in basal forebrain results in dysfunction of the cholinergic circuitry.

Authors:  Efrain Sanchez-Ortiz; Daishi Yui; Dongli Song; Yun Li; John L Rubenstein; Louis F Reichardt; Luis F Parada
Journal:  J Neurosci       Date:  2012-03-21       Impact factor: 6.167

7.  Nerve growth factor favours long-term depression over long-term potentiation in layer II-III neurones of rat visual cortex.

Authors:  Alfredo Brancucci; Nicola Kuczewski; Sonia Covaceuszach; Antonino Cattaneo; Luciano Domenici
Journal:  J Physiol       Date:  2004-07-08       Impact factor: 5.182

8.  Neurotrophin effects on survival and expression of cholinergic properties in cultured rat septal neurons under normal and stress conditions.

Authors:  D Nonner; E F Barrett; J N Barrett
Journal:  J Neurosci       Date:  1996-11-01       Impact factor: 6.167

9.  Intravenous administration of a transferrin receptor antibody-nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington disease.

Authors:  J H Kordower; V Charles; R Bayer; R T Bartus; S Putney; L R Walus; P M Friden
Journal:  Proc Natl Acad Sci U S A       Date:  1994-09-13       Impact factor: 11.205

10.  Neurotrophin 3 potentiates neuronal activity and inhibits gamma-aminobutyratergic synaptic transmission in cortical neurons.

Authors:  H G Kim; T Wang; P Olafsson; B Lu
Journal:  Proc Natl Acad Sci U S A       Date:  1994-12-06       Impact factor: 11.205
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