Trabeculotomy in the immature, enucleated human eye.

Greater than 50 per cent of resistance to aqueous outflow was eliminated by internal trabeculotomy covering 30 degrees of the limbal circumference in enucleated, postmorten infant eyes subjected to constant-pressure acqueous perfusion. The proportion of total outflow resistance eliminated after limited trabeculotomy was greater in infant eyes than that observed in eyes of older children andthan that which others have observed in adult eyes. These data suggest that in the infant eye aqueous humor may flow circumferentially in Schlemm's canal but that the capacity for circumferential flow diminishes with increasing age.