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Literature DB >> 8329279

The treatment of heart failure--what next?

Abstract

1. Despite demonstrable benefits in terms of symptomatic relief and improvement in prognosis, even the best treatments of heart failure currently available fall short of being ideal. We review the basis for newer approaches to the treatment of heart failure and discuss some of the agents which capitalize on current understanding of the underlying patho-physiology. 2. Several drugs, old and new, are presently being investigated by major clinical trials. We also consider some of the difficulties related to the design and conduct of such trials and suggest how drugs might be better assessed in the future.

Entities: Disease

Mesh：

Year: 1993 PMID： 8329279 PMCID： PMC1381595 DOI： 10.1111/j.1365-2125.1993.tb04181.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

68 in total

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Journal: Cardiovasc Res Date: 1986-02 Impact factor: 10.787

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Journal: J Cardiovasc Pharmacol Date: 1990 Impact factor: 3.105

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Authors: E Kassis; O Amtorp
Journal: J Cardiovasc Pharmacol Date: 1990-03 Impact factor: 3.105

6. Sympathoinhibitory effects of atrial natriuretic factor in normal humans.

Authors: J S Floras
Journal: Circulation Date: 1990-06 Impact factor: 29.690

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Journal: N Engl J Med Date: 1984-09-27 Impact factor: 91.245

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Authors: F X Kleber; L Niemöller; W Doering
Journal: Br Heart J Date: 1992-04

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Authors: W Culling; M S Ruttley; D J Sheridan
Journal: Br Heart J Date: 1984-10

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Authors: L Dei Cas; M Metra; S Nodari; O Visioli
Journal: J Cardiovasc Pharmacol Date: 1989 Impact factor: 3.105

1 in total

1. Acute and chronic effects of flosequinan on resting and exercise haemodynamics in congestive heart failure.

Authors: P Thomas; D J O'Gorman; D J Sheridan
Journal: Br J Clin Pharmacol Date: 1993-12 Impact factor: 4.335

1 in total