Literature DB >> 83284

Anencephaly in trisomy 18 associated with elevated alpha-1-fetoprotein in amniotic fluid.

U Merrild, V Schiøler, F Christensen, E Wolny, C J Edeling.   

Abstract

Elevated levels of alpha-1-fetoprotein (AFP) were found in the amniotic fluid of a 36-year-old woman in the 15th week of gestation. Because of this and the results of repeated ultrasonography, abortion was induced. An anencephalic fetus with trisomy 18 was delivered. The possible correlation among neural-tube defects, chromosomal abnormalities, and level of AFP is discussed.

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Year:  1978        PMID: 83284     DOI: 10.1007/BF00277578

Source DB:  PubMed          Journal:  Hum Genet        ISSN: 0340-6717            Impact factor:   4.132


  6 in total

1.  Anencephaly in trisomy 18: related or unrelated?

Authors:  M Menashi; A Ornoy; M M Cohen
Journal:  Teratology       Date:  1977-06

2.  Alpha-fetoprotein levels in amniotic fluids from spontaneous abortions.

Authors:  M J Seller; M R Creasy; E D Alberman
Journal:  Br Med J       Date:  1974-06-08

3.  Electroimmuno assay.

Authors:  C B Laurell
Journal:  Scand J Clin Lab Invest Suppl       Date:  1972

4.  Alpha-fetoprotein in the antenatal diagnosis of anencephaly and spina bifida.

Authors:  D J Brock; R G Sutcliffe
Journal:  Lancet       Date:  1972-07-29       Impact factor: 79.321

5.  Chromosome analysis of fetuses in risk pregnancies.

Authors:  J Philip; J Bang; N Hahnemann; M Mikkelsen; E Niebuhr; H Rebbe; J Weber
Journal:  Acta Obstet Gynecol Scand Suppl       Date:  1974

6.  Differential binding of alkylating fluorochromes in human chromosomes.

Authors:  T Caspersson; L Zech; C Johansson
Journal:  Exp Cell Res       Date:  1970-06       Impact factor: 3.905

  6 in total
  1 in total

1.  Congenital hydrocephalus in an Egyptian baby with trisomy 18: a case report.

Authors:  Kotb A Metwalley; Hekma S Farghalley; Alaa A Abd-Elsayed
Journal:  J Med Case Rep       Date:  2009-11-09
  1 in total

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