| Literature DB >> 8327403 |
M Antolini1, L Trevisi, P Debetto, S Luciani.
Abstract
The effect of amiloride on Na+/Ca2+ exchange activity and adenylate energy charge in isolated rat cardiac myocytes has been studied. Amiloride inhibits Na+/Ca2+ exchange activity in rat cardiac myocytes with an IC50 of 1.76 mM when added to the external side of the cell membrane, whereas it is a weaker inhibitor when present at the cytoplasmic side. The adenylate energy charge in rat cardiac myocytes is unaffected by amiloride.Entities:
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Year: 1993 PMID： 8327403 DOI： 10.1006/phrs.1993.1021
Source DB: PubMed Journal: Pharmacol Res ISSN： 1043-6618 Impact factor: 7.658