Literature DB >> 8325649

Mapping genes according to their amplification status in tumor cells: contribution to the map of 11q13.

P Szepetowski1, D Perucca-Lostanlen, P Gaudray.   

Abstract

DNA amplification events that occur at 11q13 in human carcinomas are complex, and amplicons were shown to exhibit numerous discontinuities that could be used as tools for mapping this genomic area. A statistical nearest-neighbor analysis of the amplification patterns of several 11q13 loci in a panel of amplified DNAs was performed in the region of 11q13 centromeric from BCL1. It was strongly correlated with the physical linkages that we established between the same markers. Taken together, our results led to a map of 14 genes and four anonymous probes located in this area.

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Year:  1993        PMID： 8325649     DOI： 10.1006/geno.1993.1257

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  6 in total

1.  Human EMK1 is located on 11q12-q13, close to COX8 and FTH1.

Authors:  A Courseaux; M Fernandes; J Grosgeorge; J Inglis; S D Raynaud; P Gaudray
Journal:  Mamm Genome       Date:  1995-04       Impact factor: 2.957

2.  Expression and gene amplification of primary (A, B1, D1, D3, and E) and secondary (C and H) cyclins in colon adenocarcinomas and correlation with patient outcome.

Authors:  J Bondi; A Husdal; G Bukholm; J M Nesland; A Bakka; I R K Bukholm
Journal:  J Clin Pathol       Date:  2005-05       Impact factor: 3.411

3.  High-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1, that is amplified and overexpressed in oral cancer cells.

Authors:  Xin Huang; Susanne M Gollin; Siva Raja; Tony E Godfrey
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-09       Impact factor: 11.205

4.  Genetic mapping studies of 40 loci and 23 cosmids in chromosome 11p13-11q13, and exclusion of mu-calpain as the multiple endocrine neoplasia type 1 gene.

Authors:  J T Pang; S E Lloyd; C Wooding; B Farren; B Pottinger; B Harding; S E Leigh; M A Pook; F J Benham; G T Gillett; R T Taggart; R V Thakker
Journal:  Hum Genet       Date:  1996-06       Impact factor: 4.132

Review 5.  Chromosome 11q13 markers and D-type cyclins in breast cancer.

Authors:  G Peters; V Fantl; R Smith; S Brookes; C Dickson
Journal:  Breast Cancer Res Treat       Date:  1995       Impact factor: 4.872

6.  Whole genome DNA copy number changes identified by high density oligonucleotide arrays.

Authors:  Jing Huang; Wen Wei; Jane Zhang; Guoying Liu; Graham R Bignell; Michael R Stratton; P Andrew Futreal; Richard Wooster; Keith W Jones; Michael H Shapero
Journal:  Hum Genomics       Date:  2004-05       Impact factor: 4.639
  6 in total

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