| Literature DB >> 8325389 |
M Owais1, I Ahmed, B Krishnakumar, R K Jain, B K Bachhawat, C M Gupta.
Abstract
Encapsulation of amphotericin B in tuftsin-bearing liposomes greatly increased its efficacy in treatment of human aspergillosis in mice. Also, the drug efficacy was significantly increased by pretreating the animals with drug-free tuftsin-bearing liposomes. These results demonstrate that macrophage activation can considerably enhance the therapeutic efficacy of antifungal drugs, like amphotericin B.Entities:
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Year: 1993 PMID: 8325389 DOI: 10.1016/0014-5793(93)81760-w
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124